First recognized as an occupational disorder, obliterative bronchiolitis is now the primary
noninfectious pulmonary complication of allogeneic hematopoietic stem-cell transplantation …

First performed in 1963, lung transplantation is approaching the half-century mark. With
more than 32,000 procedures having been performed worldwide, lung transplantation has …

The circulation of the lung is unique both in volume and function. For example, it is the only
organ with two circulations: the pulmonary circulation, the main function of which is gas …

Obliterative bronchiolitis (OB) is the key impediment to the long-term survival of lung
transplant recipients and the lack of a robust preclinical model precludes examining OB …

OBJECTIVES Anastomotic airway complications give rise to morbidity and mortality after
lung transplantation. Knowledge about contributing factors helps in adopting diagnostic and …

Chronic rejection, manifested as small airway fibrosis (obliterative bronchiolitis [OB]), is the
main obstacle to long-term survival in lung transplantation. Recent studies demonstrate that …

Benign central airway obstruction (CAO) is responsible for significant morbidity due to
dyspnea and impaired quality of life. While iatrogenic causes, including stenosis after …

Background Airway complications are rare and cause increased morbidity and mortality after
lung transplantation (LT). We sought to examine risk factors associated with this …

Background Although the benefits of ex vivo lung perfusion (EVLP) have been globally
advocated, the potentially deleterious effects of applying EVLP, in particular activation of …

Lung transplantation (LTx) is the gold standard treatment for end-stage lung disease;
however, waitlist mortality remains high due to a shortage of suitable donor lungs. Organ …