Photodynamic therapy (PDT) has aroused great research interest in recent years owing to its
high spatiotemporal selectivity, minimal invasiveness, and low systemic toxicity. However …

Advances in nanomedicine, including early cancer detection, targeted drug delivery, and
personalized approaches to cancer treatment are on the rise. For example, targeted drug …

Early detection and diagnosis of many cancers is very challenging. Late stage detection of a
cancer always leads to high mortality rates. It is imperative to develop novel and more …

Sonodynamic therapy (SDT) typically suffers from compromised anticancer efficacy owing to
the low reactive oxygen species (ROS) yield and complicated tumor microenvironment …

Cancer immunotherapy and vaccine development have significantly improved the fight
against cancers. Despite these advancements, challenges remain, particularly in the clinical …

Photodynamic therapy (PDT), a noninvasive cancer therapeutic method triggered by light,
would lead to severe tumor hypoxia after treatment. Utilizing a hypoxia-activated prodrug …

The complexity of the tumor microenvironment presents significant challenges to cancer
therapy, while providing opportunities for targeted drug delivery. Using characteristic signals …

Hypoxia, the typical and conspicuous characteristic of most solid tumors, worsens the tumor
invasiveness and metastasis. Here, we engineered a sequential ultrasound (US)/hypoxia …

Small-molecule prodrugs have become the main toolbox to improve the unfavorable
physicochemical properties of potential therapeutic compounds in contemporary anti-cancer …

Hypoxia, resulting from the imbalance between oxygen supply and consumption is a critical
component of the tumor microenvironment. It has a paramount impact on cancer growth …