Mechanisms of cancer cell death induction by paclitaxel: an updated review

S Zhao, Y Tang, R Wang, M Najafi - Apoptosis, 2022 - Springer
Chemoresistance of cancer cells is a major problem in treating cancer. Knowledge of how
cancer cells may die or resist cancer drugs is critical to providing certain strategies to …

[HTML][HTML] The role of epigenetic modifications in human cancers and the use of natural compounds as epidrugs: Mechanistic pathways and pharmacodynamic actions

A Bouyahya, H Mechchate, L Oumeslakht, I Zeouk… - Biomolecules, 2022 - mdpi.com
Cancer is a complex disease resulting from the genetic and epigenetic disruption of normal
cells. The mechanistic understanding of the pathways involved in tumor transformation has …

[HTML][HTML] Resveratrol in breast cancer treatment: from cellular effects to molecular mechanisms of action

M Behroozaghdam, M Dehghani, A Zabolian… - Cellular and Molecular …, 2022 - Springer
Breast cancer (BC) is one of the most common cancers in females and is responsible for the
highest cancer-related deaths following lung cancer. The complex tumor microenvironment …

Resveratrol in cancer therapy: from stimulation of genomic stability to adjuvant cancer therapy: a comprehensive review

P Amini, R Moazamiyanfar, MS Dakkali… - Current topics in …, 2023 - ingentaconnect.com
Cancer therapy through anticancer drugs and radiotherapy is associated with several side
effects as well as tumor resistance to therapy. The genotoxic effects of chemotherapy and …

Modulation of the immune system by melatonin; implications for cancer therapy

M Moslehi, R Moazamiyanfar, MS Dakkali… - International …, 2022 - Elsevier
Immune system interactions within the tumour have a key role in the resistance or
sensitization of cancer cells to anti-cancer agents. On the other hand, activation of the …

Nobiletin as an inducer of programmed cell death in cancer: a review

J Huang, Z Chang, Q Lu, X Chen, M Najafi - Apoptosis, 2022 - Springer
Cancer resistance to therapy is a big issue in cancer therapy. Tumours may develop some
mechanisms to reduce the induction of cell death, thus stimulating tumour growth. Cancer …

Apigenin in cancer therapy: Prevention of genomic instability and anticancer mechanisms

M Moslehi, S Rezaei, P Talebzadeh… - Clinical and …, 2023 - Wiley Online Library
The incidence of cancer has been growing worldwide. Better survival rates following the
administration of novel drugs and new combination therapies may concomitantly cause …

Tumor microenvironment remodeling in oral cancer: Application of plant derived-natural products and nanomaterials

HS Budi, B Farhood - Environmental research, 2023 - Elsevier
Oral cancers consist of squamous cell carcinoma (SCC) and other malignancies in the
mouth with varying degrees of invasion and differentiation. For many years, different …

Immunoregulation by resveratrol; implications for normal tissue protection and tumour suppression

AR Lalani, F Fakhari, S Radgoudarzi… - Clinical and …, 2023 - Wiley Online Library
Immune reactions are involved in both tumour and normal tissue in response to therapy.
Elevated secretion of certain chemokines, exosomes and cytokines triggers inflammation …

Mechanisms of cancer cell killing by metformin: a review on different cell death pathways

X Wu, WW Xu, X Huan, G Wu, G Li, YH Zhou… - Molecular and cellular …, 2023 - Springer
Cancer resistance to anti-tumour agents has been one of the serious challenges in different
types of cancer treatment. Usually, an increase in the cell death markers can predict a higher …