As a result of their unique physical properties, biological membrane mimetics, such as
liposomes, are used in a broad range of scientific and technological applications …

The β-barrel is a transmembrane structural motif commonly encountered in bacterial outer
membrane proteins and pore-forming toxins (PFTs). α-Hemolysin (αHL) is a cytotoxin …

To determine how the lipid environment affects membrane protein structure and function,
strains of Escherichia coli were developed in which normal phospholipid composition can …

Delineating the folding steps of helical-bundle membrane proteins has been a challenging
task. Many questions remain unanswered, including the conformation and stability of the …

The advantages of targeted therapy have motivated many efforts to find distinguishing
features between the molecular cell surface landscapes of diseased and normal cells …

The interaction of small molecules with lipid membranes and the exact knowledge of their
binding site and bilayer distribution is of great pharmacological importance and represents …

We have examined the role of the environment on the interactions between transmembrane
helices using, as a model system, the dimerization of the glycophorin A transmembrane …

Cardiolipin is an anionic lipid found in the mitochondrial membranes of eukaryotes ranging
from unicellular microorganisms to metazoans. This unique lipid contributes to various …

As the number of membrane proteins in the Protein Data Bank increases, efforts to
understand how they interact with their natural environment are increasing in importance. A …

The crystal structure of rhodopsin provides significant insights concerning structure/activity
relationships in visual pigments and related G-protein-coupled receptors. The specific …