Pre-eclampsia

BWJ Mol, CT Roberts, S Thangaratinam, LA Magee… - The Lancet, 2016 - thelancet.com
Summary Pre-eclampsia affects 3–5% of pregnancies and is traditionally diagnosed by the
combined presentation of high blood pressure and proteinuria. New definitions also include …

Pregnancy characteristics and women's future cardiovascular health: an underused opportunity to improve women's health?

JW Rich-Edwards, A Fraser, DA Lawlor… - Epidemiologic …, 2014 - academic.oup.com
Growing evidence indicates that women with a history of common pregnancy complications,
including fetal growth restriction and preterm delivery (often combined as low birth weight) …

Pre-eclampsia and future cardiovascular risk among women: a review

R Ahmed, J Dunford, R Mehran, S Robson… - Journal of the American …, 2014 - jacc.org
Cardiovascular disease continues to be the leading cause of death in the western world.
Due to advancements in diagnosis, prevention, and treatment, cardiovascular mortality has …

Maternal obesity is associated with dysregulation of metabolic, vascular, and inflammatory pathways

JE Ramsay, WR Ferrell, L Crawford… - The Journal of …, 2002 - academic.oup.com
Obesity is increasing in prevalence worldwide and in all age groups. In nonpregnant
individuals, obesity is associated with dyslipidemia; hyperinsulinemia; vascular dysfunction; …

Intermediate metabolism in normal pregnancy and in gestational diabetes

G Di Cianni, R Miccoli, L Volpe… - Diabetes/metabolism …, 2003 - Wiley Online Library
Complex though integrated hormonal and metabolic changes characterize pregnancy. In the
face of progressive decline in insulin action, glucose homeostasis is maintained through a …

Oxidative stress in the pathogenesis of preeclampsia

CA Hubel - Proceedings of the Society for Experimental …, 1999 - Wiley Online Library
The etiology and pathogenesis of the pregnancy syndrome preeclampsia remain poorly
understood. There is substantial evidence to suggest that the diverse manifestations of …

Recent insights into the pathogenesis of pre-eclampsia

JM Roberts, KY Lain - Placenta, 2002 - Elsevier
Pre-eclampsia is more than pregnancy induced hypertension. The emerging view described
in this presentation is that pre-eclampsia is secondary to the interactions of reduced …

Molecular mechanisms of maternal vascular dysfunction in preeclampsia

S Goulopoulou, ST Davidge - Trends in molecular medicine, 2015 - cell.com
In preeclampsia, as a heterogeneous syndrome, multiple pathways have been proposed for
both the causal as well as the perpetuating factors leading to maternal vascular dysfunction …

Fatty acid oxidation disorders

P Rinaldo, D Matern, MJ Bennett - Annual review of physiology, 2002 - annualreviews.org
▪ Abstract Genetic disorders of mitochondrial fatty acid β-oxidation have been recognized
within the last 20 years as important causes of morbidity and mortality, highlighting the …

Maternal periodontal disease is associated with an increased risk for preeclampsia

KA Boggess, S Lieff, AP Murtha, K Moss… - Obstetrics & …, 2003 - journals.lww.com
METHODS A cohort of 1115 healthy pregnant women were enrolled at less than 26 weeks'
gestation and followed until delivery. Maternal demographic and medical data were …