Paracrine mechanisms of mesenchymal stromal cells in angiogenesis

S Maacha, H Sidahmed, S Jacob… - Stem cells …, 2020 - Wiley Online Library
The role of the mesenchymal stromal cell‐(MSC‐) derived secretome is becoming
increasingly intriguing from a clinical perspective due to its ability to stimulate endogenous …

On the choice of the extracellular vesicles for therapeutic purposes

C Campanella, C Caruso Bavisotto, M Logozzi… - International journal of …, 2019 - mdpi.com
Extracellular vesicles (EVs) are lipid membrane vesicles released by all human cells and
are widely recognized to be involved in many cellular processes, both in physiological and …

Mesenchymal stem cell-derived extracellular vesicles attenuate influenza virus-induced acute lung injury in a pig model

M Khatri, LA Richardson, T Meulia - Stem cell research & therapy, 2018 - Springer
Background Mesenchymal stem (stromal) cells (MSCs) mediate their immunoregulatory and
tissue repair functions by secreting paracrine factors, including extracellular vesicles (EVs) …

Mesenchymal stromal cell-derived extracellular vesicles attenuate dendritic cell maturation and function

M Reis, E Mavin, L Nicholson, K Green… - Frontiers in …, 2018 - frontiersin.org
Mesenchymal stromal cells (MSCs) are potent regulators of immune responses largely
through paracrine signaling. MSC secreted extracellular vesicles (MSC-EVs) are …

Renal regenerative potential of different extracellular vesicle populations derived from bone marrow mesenchymal stromal cells

S Bruno, M Tapparo, F Collino, G Chiabotto… - … Engineering Part A, 2017 - liebertpub.com
Extracellular vesicles (EVs) derived from human bone marrow mesenchymal stromal cells
(MSCs) promote the regeneration of kidneys in different animal models of acute kidney …

The role of bone marrow mesenchymal stem cell derived extracellular vesicles (MSC-EVs) in normal and abnormal hematopoiesis and their therapeutic potential

AK Batsali, A Georgopoulou, I Mavroudi… - Journal of Clinical …, 2020 - mdpi.com
Mesenchymal stem cells (MSCs) represent a heterogeneous cellular population responsible
for the support, maintenance, and regulation of normal hematopoietic stem cells (HSCs). In …

The long and short of it: the emerging roles of non-coding RNA in small extracellular vesicles

A Abramowicz, MD Story - Cancers, 2020 - mdpi.com
Small extracellular vesicles (EVs) play a significant role in intercellular communication
through their non-coding RNA (ncRNA) cargo. While the initial examination of EV cargo …

[HTML][HTML] Non-coding RNAs in mesenchymal stem cell-derived extracellular vesicles: deciphering regulatory roles in stem cell potency, inflammatory resolve, and tissue …

F Fatima, K Ekstrom, I Nazarenko, M Maugeri… - Frontiers in …, 2017 - frontiersin.org
Extracellular vesicles (EVs) are heterogeneous populations of nano-and micro-sized
vesicles secreted by various cell types. There is mounting evidence that EVs have …

Hematopoietic stem and progenitor cell signaling in the niche

SN Hurwitz, SK Jung, P Kurre - Leukemia, 2020 - nature.com
Hematopoietic stem and progenitor cells (HSPCs) are responsible for lifelong maintenance
of hematopoiesis through self-renewal and differentiation into mature blood cell lineages …

Mesenchymal stromal cells: role in the BM niche and in the support of hematopoietic stem cell transplantation

S Crippa, ME Bernardo - Hemasphere, 2018 - journals.lww.com
Mesenchymal stromal cells (MSCs) are key elements in the bone marrow (BM) niche where
they interact with hematopoietic stem progenitor cells (HSPCs) by offering physical support …