Novel biomarkers, oxidative stress, and the role of labile iron toxicity in cardiopulmonary bypass-associated acute kidney injury

M Haase, R Bellomo, A Haase-Fielitz - Journal of the American College of …, 2010 - jacc.org
Cardiac surgery-associated acute kidney injury (AKI) is common and carries a poor
prognosis. Hemodynamic and inflammatory factors and the release of labile iron …

Biomarkers of drug-induced acute kidney injury in the adult

GC Gobe, JS Coombes, RG Fassett… - Expert opinion on drug …, 2015 - Taylor & Francis
Introduction: This article addresses general biomarkers of drug-induced acute kidney injury
(AKI) and their application in development and progression of AKI in the adult. It also …

[HTML][HTML] The role of podocyte damage in the etiology of ischemia-reperfusion acute kidney injury and post-injury fibrosis

Y Chen, L Lin, X Tao, Y Song, J Cui, J Wan - BMC nephrology, 2019 - Springer
Background To establish a model of chronic renal fibrosis following acute kidney injury (AKI)
in BALB/c mice and to observe the effect of AKI on podocyte injury and chronic fibrosis of the …

A fully human anti-hepcidin antibody modulates iron metabolism in both mice and nonhuman primates

KS Cooke, B Hinkle, H Salimi-Moosavi… - Blood, The Journal …, 2013 - ashpublications.org
Iron maldistribution has been implicated in the etiology of many diseases including the
anemia of inflammation (AI), atherosclerosis, diabetes, and neurodegenerative disorders …

[HTML][HTML] Lactoferrin contributes a renoprotective effect in acute kidney injury and early renal fibrosis

YH Hsu, IJ Chiu, YF Lin, YJ Chen, YH Lee, HW Chiu - Pharmaceutics, 2020 - mdpi.com
Patients with acute kidney injury (AKI) who survive the acute stage are at notable risk for
chronic kidney disease (CKD) progression. There is no single therapy that can effectively …

Plasma element levels and risk of chronic kidney disease in elderly populations (≥ 90 Years old)

Y Shen, Z Yin, Y Lv, J Luo, W Shi, J Fang, X Shi - Chemosphere, 2020 - Elsevier
Associations between plasma elements and chronic kidney disease (CKD) among the
elderly are poorly understood. In this cross-sectional study, we explored the associations …

[HTML][HTML] Enhancing the expression of a key mitochondrial enzyme at the inception of ischemia-reperfusion injury can boost recovery and halt the progression of acute …

PR Corridon - Frontiers in Physiology, 2023 - frontiersin.org
Hydrodynamic fluid delivery has shown promise in influencing renal function in disease
models. This technique provided pre-conditioned protection in acute injury models by …

[HTML][HTML] Role of SIK1 in the transition of acute kidney injury into chronic kidney disease

J Hu, J Qiao, Q Yu, B Liu, J Zhen, Y Liu, Q Ma… - Journal of Translational …, 2021 - Springer
Background Acute kidney injury (AKI), with a high morbidity and mortality, is recognized as a
risk factor for chronic kidney disease (CKD). AKI-CKD transition has been regarded as one …

[HTML][HTML] Sodium oxalate-induced acute kidney injury associated with glomerular and tubulointerstitial damage in rats

L de Araújo, JM Costa-Pessoa, MC De Ponte… - Frontiers in …, 2020 - frontiersin.org
Acute crystalline nephropathy is closely related to tubulointerstitial injury, but few studies
have investigated glomerular changes in this condition. Thus, in the current study, we …

Serum iron level and kidney function: a Mendelian randomization study

F Del Greco M, L Foco, I Pichler, P Eller… - Nephrology Dialysis …, 2017 - academic.oup.com
Background: Iron depletion is a known consequence of chronic kidney disease (CKD), but
there is contradicting epidemiological evidence on whether iron itself affects kidney function …