[HTML][HTML] Clinical tools and biomarkers to predict preeclampsia

TM MacDonald, SP Walker, NJ Hannan, S Tong… - …, 2022 - thelancet.com
Preeclampsia is pregnancy-specific, and significantly contributes to maternal, and perinatal
morbidity and mortality worldwide. An effective predictive test for preeclampsia would …

Identification of biomarkers for preeclampsia based on metabolomics

M Yao, Y Xiao, Z Yang, W Ge, F Liang, H Teng… - Clinical …, 2022 - Taylor & Francis
Background Preeclampsia (PE) is a significant cause of maternal and neonatal morbidity
and mortality worldwide. However, the pathogenesis of PE is unclear and reliable early …

Multivariable prediction models for fetal macrosomia and large for gestational age: A systematic review

L Ewington, N Black, C Leeson… - … Journal of Obstetrics …, 2024 - Wiley Online Library
Background The identification of large for gestational age (LGA) and macrosomic fetuses is
essential for counselling and managing these pregnancies. Objectives To systematically …

[HTML][HTML] Association between fetal abdominal growth trajectories, maternal metabolite signatures early in pregnancy, and childhood growth and adiposity: prospective …

J Villar, R Ochieng, RB Gunier… - The Lancet Diabetes & …, 2022 - thelancet.com
Background Obesity predominantly affects populations in high-income countries and those
countries facing epidemiological transition. The risk of childhood obesity is increased among …

Metabolomic identification of a novel, externally validated predictive test for gestational diabetes mellitus

U Sovio, GL Clayton, E Cook, F Gaccioli… - The Journal of …, 2022 - academic.oup.com
Context Undiagnosed gestational diabetes mellitus (GDM) is a major preventable cause of
stillbirth. In the United Kingdom, women are selected for diagnostic testing for GDM based …

Advances in preeclampsia testing.

JJ Miller, V Higgins, A Ren, S Logan… - Advances in Clinical …, 2023 - europepmc.org
Preeclampsia is a multisystem hypertensive disorder and one of the leading causes of
maternal and fetal morbidity and mortality. The clinical hallmarks such as hypertension and …

[HTML][HTML] Effect of common pregnancy and perinatal complications on offspring metabolic traits across the life course: a multi-cohort study

A Elhakeem, J Ronkainen, T Mansell, K Lange… - BMC medicine, 2023 - Springer
Background Common pregnancy and perinatal complications are associated with offspring
cardiometabolic risk factors. These complications may influence multiple metabolic traits in …

[HTML][HTML] Social inequalities in pregnancy metabolic profile: findings from the multi-ethnic Born in Bradford cohort study

A Elhakeem, GL Clayton, AG Soares, K Taylor… - BMC Pregnancy and …, 2024 - Springer
Background Lower socioeconomic position (SEP) associates with adverse pregnancy and
perinatal outcomes and with less favourable metabolic profile in nonpregnant adults …

Prediction of spontaneous preterm birth using supervised machine learning on metabolomic data: A case–cohort study

Y Al Ghadban, Y Du… - … Journal of Obstetrics …, 2024 - Wiley Online Library
Objectives To identify and internally validate metabolites predictive of spontaneous preterm
birth (sPTB) using multiple machine learning methods and sequential maternal serum …

[HTML][HTML] The relationship of maternal gestational mass spectrometry-derived metabolites with offspring congenital heart disease: results from multivariable and …

K Taylor, N McBride, J Zhao, S Oddie, R Azad… - Journal of …, 2022 - mdpi.com
Background: It is plausible that maternal pregnancy metabolism influences the risk of
offspring congenital heart disease (CHD). We sought to explore this through a systematic …