[HTML][HTML] Transcytosis-Driven Treatment of Neurodegenerative Disorders by mRNA-Expressed Antibody–Transferrin Conjugates

SK Niazi, M Magoola - Biomedicines, 2024 - mdpi.com
The recent setbacks in the withdrawal and approval delays of antibody treatments of
neurodegenerative disorders (NDs), attributed to their poor entry across the blood–brain …

[HTML][HTML] Rationally Designed Novel Antimicrobial Peptides Targeting Chitin Synthase for Combating Soybean Phytophthora Blight

Y Ran, K Shehzadi, JH Liang, MJ Yu - International Journal of Molecular …, 2024 - mdpi.com
Soybean phytophthora blight is a severe menace to global agriculture, causing annual
losses surpassing USD 1 billion. Present crop loss mitigation strategies primarily rely on …

StreaMD: the toolkit for high-throughput molecular dynamics simulations

A Ivanova, O Mokshyna, P Polishchuk - 2024 - chemrxiv.org
Molecular dynamics simulations serve as a prevalent approach for investigating the dynamic
behaviour of proteins and protein-ligand complexes. Due to its versatility and speed …