Early‐onset colorectal cancer in young individuals

G Mauri, A Sartore‐Bianchi, AG Russo… - Molecular …, 2019 - Wiley Online Library
Treatment of young adults with colorectal cancer (CRC) represents an unmet clinical need,
especially as diagnosis in this population might lead to the greatest loss of years of life …

[HTML][HTML] Early-onset colorectal cancer: A review of current knowledge

MR Saraiva, I Rosa, I Claro - World journal of gastroenterology, 2023 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is one of the most prevalent malignancies worldwide. Although
most prevalent among older people, its incidence above 50 years old has been decreasing …

Early-onset colorectal cancer: initial clues and current views

LJ Hofseth, JR Hebert, A Chanda, H Chen… - Nature reviews …, 2020 - nature.com
Over the past several decades, the incidence of early-onset colorectal cancer (EOCRC; in
patients< 50 years old) has increased at an alarming rate. Although robust and scientifically …

Colorectal cancer in the young: epidemiology, prevention, management.

RL Siegel, CD Jakubowski, SA Fedewa… - American Society of …, 2020 - europepmc.org
Colorectal cancer (CRC) incidence rates in the United States overall have declined since
the mid-1980s because of changing patterns in risk factors (eg, decreased smoking) and …

[HTML][HTML] Delphi initiative for early-onset colorectal cancer (DIRECt) international management guidelines

GM Cavestro, A Mannucci, F Balaguer… - Clinical …, 2023 - Elsevier
Background & Aims Patients with early-onset colorectal cancer (eoCRC) are managed
according to guidelines that are not age-specific. A multidisciplinary international group …

Analysis of survival among adults with early-onset colorectal cancer in the National Cancer Database

E Cheng, HN Blackburn, K Ng, D Spiegelman… - JAMA network …, 2021 - jamanetwork.com
Importance While increased adherence to colorectal cancer (CRC) screening guidelines in
the US has been associated with significant reductions in cancer incidence in US individuals …

Epidemiology of microsatellite instability high (MSI‐H) and deficient mismatch repair (dMMR) in solid tumors: a structured literature review

M Lorenzi, M Amonkar, J Zhang, S Mehta… - Journal of …, 2020 - Wiley Online Library
Background. Given limited data on the epidemiology of MSI‐H and dMMR across solid
tumors (except colorectal cancer (CRC)), the current study was designed to estimate their …

Emerging cancer incidence trends in Canada: the growing burden of young adult cancers

EV Heer, AS Harper, H Sung, A Jemal… - Cancer, 2020 - Wiley Online Library
Background Recent studies have identified increases in cancer incidence among younger
adults for some cancers. This study examined incidence trends for 28 cancers in Canada by …

Epidemiology and outcomes of young-onset esophageal adenocarcinoma: an analysis from a population-based database

DC Codipilly, T Sawas, L Dhaliwal, ML Johnson… - … Biomarkers & Prevention, 2021 - AACR
Background: Esophageal adenocarcinoma is a lethal cancer with rising incidence. There
are limited data in younger (< 50 years) patients with esophageal adenocarcinoma. We …

Early onset sporadic colorectal cancer: Worrisome trends and oncogenic features

GM Cavestro, A Mannucci, RA Zuppardo… - Digestive and liver …, 2018 - Elsevier
Early onset colorectal cancers, defined as arising before 50 years of age, are a growing
health hazard in western and eastern countries alike. The incidence of colon and rectal …