Dementia prevention, intervention, and care: 2020 report of the Lancet Commission

G Livingston, J Huntley, A Sommerlad, D Ames… - The Lancet, 2020 - thelancet.com
Executive summary The number of older people, including those living with dementia, is
rising, as younger age mortality declines. However, the age-specific incidence of dementia …

Alzheimer's disease; a review of the pathophysiological basis and therapeutic interventions

A Abeysinghe, R Deshapriya, C Udawatte - Life sciences, 2020 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disorder and is identified as the most
common cause for dementia. Despite huge global economic burden and the impact on the …

A national cohort study (2000–2018) of long-term air pollution exposure and incident dementia in older adults in the United States

L Shi, K Steenland, H Li, P Liu, Y Zhang… - Nature …, 2021 - nature.com
Air pollution may increase risk of Alzheimer's disease and related dementias (ADRD) in the
US, but the extent of this relationship is unclear. Here, we constructed two national US …

[HTML][HTML] Alzheimer disease pathogenesis: insights from molecular and cellular biology studies of oligomeric Aβ and tau species

XQ Chen, WC Mobley - Frontiers in Neuroscience, 2019 - frontiersin.org
Alzheimer disease (AD) represents an oncoming epidemic that without an effective
treatment promises to exact extraordinary human and financial burdens. Studies of …

Alcohol use and dementia: a systematic scoping review

J Rehm, OSM Hasan, SE Black, KD Shield… - Alzheimer's research & …, 2019 - Springer
Background Alcohol use has been identified as a risk factor for dementia and cognitive
decline. However, some patterns of drinking have been associated with beneficial effects …

Tau proteins and tauopathies in Alzheimer's disease

FP Chong, KY Ng, RY Koh, SM Chye - Cellular and molecular …, 2018 - Springer
Alzheimer's disease (AD) is characterized by progressive memory loss and cognitive
function deficits. There are two major pathological hallmarks that contribute to the …

Diet in the prevention of Alzheimer's disease: current knowledge and future research requirements

O Stefaniak, M Dobrzyńska, S Drzymała-Czyż… - Nutrients, 2022 - mdpi.com
Alzheimer's disease is a progressive brain disease that is becoming a major health problem
in today's world due to the aging population. Despite it being widely known that diet has a …

Promoting successful cognitive aging: a ten-year update

TJ Krivanek, SA Gale, BM McFeeley… - Journal of …, 2021 - content.iospress.com
A decade has passed since we published a comprehensive review in this journal
addressing the topic of promoting successful cognitive aging, making this a good time to …

Blood cholesterol and risk of dementia in more than 1· 8 million people over two decades: a retrospective cohort study

M Iwagami, N Qizilbash, J Gregson… - The Lancet Healthy …, 2021 - thelancet.com
Background Uncertainty remains concerning the association of blood cholesterol with the
risk of subsequent dementia. Using data from people with lipid measurements in the UK …

The role of sex and sex hormones in neurodegenerative diseases

E Vegeto, A Villa, S Della Torre, V Crippa… - Endocrine …, 2020 - academic.oup.com
Neurodegenerative diseases (NDs) are a wide class of disorders of the central nervous
system (CNS) with unknown etiology. Several factors were hypothesized to be involved in …