Morroniside interaction with poly (ADP-ribose) polymerase accentuates metabolic mitigation of alloxan-induced genotoxicity and hyperglycaemia: a molecular docking …

S Dey, I Nagpal, P Sow, R Dey… - Journal of …, 2023 - Taylor & Francis
The present study tends to evaluate the possible potential of bio-active Morroniside (MOR),
against alloxan (ALX)-induced genotoxicity and hyperglycaemia. In silico prediction …

To explore the putative molecular targets of diabetic nephropathy and their inhibition utilizing potential phytocompounds

B Bhattacharjee, A Chakrovorty… - Current Medicinal …, 2024 - ingentaconnect.com
Background: This review critically addresses the putative molecular targets of Diabetic
Nephropathy (DN) and screens effective phytocompounds that can be therapeutically …

Phytochemical composition and biological activity of native Australian ginger (Alpinia caerulea)

JB Johnson, RJ Batley, JS Mani, R du Preez… - Journal of Food …, 2024 - Springer
The edible, endemic Australian species Alpinia caerulea belongs to the same family as
ginger and turmeric. The rhizome and fruit have a mild ginger-like flavour, but there is very …

Gentiopicroside ameliorates glucose and lipid metabolism in T2DM via targeting FGFR1

Z Xu, J Huang, M Wen, X Zhang, D Lyu, S Li, H Xiao… - Phytomedicine, 2024 - Elsevier
Background The suppression of the fibroblast growth factor 21/fibroblast growth factor
receptor 1 (FGF21/FGFR1) signaling pathway is considered as a vital factor in the type 2 …

[HTML][HTML] Novel brain-penetrant inhibitor of G9a methylase blocks Alzheimer's disease proteopathology for precision medication

X Chen, L Xie, R Sheehy, Y Xiong, A Muneer… - Research …, 2023 - ncbi.nlm.nih.gov
Current amyloid beta-targeting approaches for Alzheimer's disease (AD) therapeutics only
slow cognitive decline for small numbers of patients. This limited efficacy exists because AD …

Pre-clinical study of the bioactive compound Asiaticoside against the proteins inducing human mammary carcinoma using molecular docking and ADME analysis

A Bilal, F Tanvir, S Ahmad, SHA Shah… - Remittances …, 2024 - remittancesreview.com
The objective of this study is to identify the pharmacokinetics properties of a bioactive
compound of asiaticoside and its effects on breast cancer inducing proteins. For this …