Synaptic dysfunction connects autism spectrum disorder and sleep disturbances: A perspective from studies in model organisms

F Doldur-Balli, T Imamura, OJ Veatch, NN Gong… - Sleep medicine …, 2022 - Elsevier
Sleep disturbances (SD) accompany many neurodevelopmental disorders, suggesting SD is
a transdiagnostic process that can account for behavioral deficits and influence underlying …

Zebrafish embryonically exposed to valproic acid present impaired retinal development and sleep behavior

L DeOliveira‐Mello, D Baronio, P Panula - Autism Research, 2023 - Wiley Online Library
Prenatal exposure to valproic acid (VPA), a drug widely used to treat epilepsy and bipolar
disorder, is an environmental risk factor for autism spectrum disorder (ASD). VPA has been …

Assessing Anti-Social and Aggressive Behavior in a Zebrafish (Danio rerio) Model of Parkinson's Disease Chronically Exposed to Rotenone

OD Ilie, R Duta, R Jijie, IB Nita, M Nicoara, C Faggio… - Brain Sciences, 2022 - mdpi.com
Background: Rotenone (ROT) is currently being used in various research fields, especially
neuroscience. Separated from other neurotoxins, ROT induces a Parkinson's disease (PD) …

[HTML][HTML] Oxytocin protective effects on zebrafish larvae models of autism-like spectrum disorder

H Rahmati-Holasoo, AS Maghsoudi… - Iranian Journal of …, 2023 - ncbi.nlm.nih.gov
Objective (s): Autism is a complicated neurodevelopmental disorder characterized by social
interaction deficiencies, hyperactivity, anxiety, communication disorders, and a limited range …

[PDF][PDF] Cannabidiol mitigates valproic acid-induced developmental toxicity and locomotor behavioral impairment in zebrafish

R Licitra, D Damiani, V Naef, B Fronte… - J. Biol. Regul …, 2023 - researchgate.net
Background: Valproic acid (VPA), an anticonvulsant used in epilepsy, has deleterious effects
on embryonic development and is considered an environmental risk factor for autism …

Toxicological Response of Zebrafish Exposed to Cocktails of Polymeric Materials and Valproic Acid

A Savuca, IA Chelaru, IM Balmus, AS Curpan… - Sustainability, 2024 - mdpi.com
Microplastic pollution represents an emerging problem of great interest in the public domain
in the last decade; in addition, it overlaps with another delicate problem—pollution with …

[HTML][HTML] Finding a Proper Valproic Acid-Based Autism Spectrum Disorder Model in Zebrafish: Early and Long-term Neurobehavioral Studies

Z Karimi, A Zarifkar, M Dianatpour, E Mirzaei… - Iranian Journal of …, 2023 - brieflands.com
Background: Valproic acid (VPA), which is often used to treat epilepsy, causes a variety of
neurobehavioral impairments that closely resemble the phenotype of autism spectrum …

Nanosilibinin ameliorates anxiety, learning impairment and Wnt-β catenin related genes expression deficits in zebrafish model of Autism Spectrum Disorder

Z Karimi, A Zarifkar, M Dianatpour, E Mirzaei, M Dara… - 2022 - researchsquare.com
purpose The present study evaluated the effect of Nanosilibinin (as an inhibitor of Wnt
signaling pathway), on neurobehavioral and molecular deficits in Valproic acid zebrafish …

The Genetics of Sleep in Zebrafish

A Zimmerman - Genetics of Sleep and Sleep Disorders, 2024 - Springer
Danio rerio (zebrafish) has become a popular model for assaying a variety of conserved
behaviors and traits. As a simple vertebrate, zebrafish provide insight into development of …

PRELIMINARY FINDINGS ON THE EFFECT OF VITAMIN B6 ON ZEBRAFISH SOCIAL BEHAVIOR

GE CHELE, A PETROVICI, R LEFTER… - The Medical-Surgical …, 2024 - revmedchir.ro
Abstract Vitamin B 6 (vit. B 6) is one of the most important vitamins involved in the
maintenance and promotion of a good state of health and body function. Needed in multiple …