The contribution of copy number variants to psychiatric symptoms and cognitive ability

J Mollon, L Almasy, S Jacquemont, DC Glahn - Molecular psychiatry, 2023 - nature.com
Copy number variants (CNVs) are deletions and duplications of DNA sequence. The most
frequently studied CNVs, which are described in this review, are recurrent CNVs that occur …

The role of RDoC in future classification of mental disorders

BN Cuthbert - Dialogues in Clinical Neuroscience, 2020 - Taylor & Francis
The Research Domain Criteria (RDoC) project constitutes a translational framework for
psychopathology research, initiated by the National Institute of Mental Health in an attempt …

Genetic influence on cognitive development between childhood and adulthood

J Mollon, EEM Knowles, SR Mathias, R Gur… - Molecular …, 2021 - nature.com
Successful cognitive development between childhood and adulthood has important
consequences for future mental and physical wellbeing, as well as occupational and …

Heritability and cognitive relevance of structural brain controllability

WH Lee, A Rodrigue, DC Glahn, DS Bassett… - Cerebral …, 2020 - academic.oup.com
Cognition and behavior are thought to emerge from the connections and interactions among
brain regions. The precise nature of these relationships remains elusive. Here we use tools …

Person-based brain morphometric similarity is heritable and correlates with biological features

GE Doucet, DA Moser, A Rodrigue, DS Bassett… - Cerebral …, 2019 - academic.oup.com
The characterization of the functional significance of interindividual variation in brain
morphometry is a core aim of cognitive neuroscience. Prior research has focused on …

Validation of the cognitive section of the Penn computerized adaptive test for neurocognitive and clinical psychopathology assessment (CAT-CCNB)

A Di Sandro, TM Moore, E Zoupou, KP Kennedy… - Brain and Cognition, 2024 - Elsevier
Abstract Background The Penn Computerized Neurocognitive Battery is an efficient tool for
assessing brain-behavior domains, and its efficiency was augmented via computerized …

Genome-wide association study of population-standardised cognitive performance phenotypes in a rural South African community

CC Soo, JT Brandenburg, A Nebel, S Tollman… - Communications …, 2023 - nature.com
Cognitive function is an indicator for global physical and mental health, and cognitive
impairment has been associated with poorer life outcomes and earlier mortality. A standard …

Integration of GWAS and brain transcriptomic analyses in a multiethnic sample of 35,245 older adults identifies DCDC2 gene as predictor of episodic memory …

Y Gao, D Felsky, D Reyes‐Dumeyer… - Alzheimer's & …, 2022 - Wiley Online Library
Identifying genes underlying memory function will help characterize cognitively resilient and
high‐risk declining subpopulations contributing to precision medicine strategies. We …

Association Study of a Comprehensive Panel of Neuropeptide-Related Polymorphisms Suggest Potential Roles in Verbal Learning and Memory

N Avgan, HG Sutherland, RA Lea, LM Haupt… - Genes, 2023 - mdpi.com
Neuropeptides are mostly expressed in regions of the brain responsible for learning and
memory and are centrally involved in cognitive pathways. The majority of neuropeptide …

General intelligence and executive functioning are overlapping but separable at genetic and molecular pathway levels: An analytical review of existing GWAS findings

LG Ciobanu, L Stankov, KO Schubert, AT Amare… - Plos one, 2022 - journals.plos.org
Understanding the genomic architecture and molecular mechanisms of cognitive functioning
in healthy individuals is critical for developing tailored interventions to enhance cognitive …