Incidence, mortality, survival, risk factor and screening of colorectal cancer: A comparison among China, Europe, and northern America

N Li, B Lu, C Luo, J Cai, M Lu, Y Zhang, H Chen, M Dai - Cancer letters, 2021 - Elsevier
Colorectal cancer (CRC) is one of the most common malignancies worldwide. China,
Europe and northern America account for more than half of the new CRC cases and …

[HTML][HTML] The intestinal microbiota and colorectal cancer

Y Cheng, Z Ling, L Li - Frontiers in immunology, 2020 - frontiersin.org
The intestinal microbiota, composed of a large population of microorganisms, is often
considered a “forgotten organ” in human health and diseases. Increasing evidence indicates …

[HTML][HTML] Causal relationship between gut microbiota and cancers: a two-sample Mendelian randomisation study

Y Long, L Tang, Y Zhou, S Zhao, H Zhu - BMC medicine, 2023 - Springer
Background Evidence from observational studies and clinical trials suggests that the gut
microbiota is associated with cancer. However, the causal association between gut …

[HTML][HTML] High-fat diet promotes colorectal tumorigenesis through modulating gut microbiota and metabolites

J Yang, H Wei, Y Zhou, CH Szeto, C Li, Y Lin… - Gastroenterology, 2022 - Elsevier
Background and Aims Dietary fat intake is associated with increased risk of colorectal
cancer (CRC). We examined the role of high-fat diet (HFD) in driving CRC through …

Killing tumor-associated bacteria with a liposomal antibiotic generates neoantigens that induce anti-tumor immune responses

M Wang, B Rousseau, K Qiu, G Huang, Y Zhang… - Nature …, 2023 - nature.com
Increasing evidence implicates the tumor microbiota as a factor that can influence cancer
progression. In patients with colorectal cancer (CRC), we found that pre-resection antibiotics …

Fusobacterium nucleatum, a key pathogenic factor and microbial biomarker for colorectal cancer

N Wang, JY Fang - Trends in Microbiology, 2023 - cell.com
Colorectal cancer (CRC), one of the most prevalent cancers, has complex etiology. The
dysbiosis of intestinal bacteria has been highlighted as an important contributor to CRC …

Ganoderma lucidum polysaccharide modulates gut microbiota and immune cell function to inhibit inflammation and tumorigenesis in colon

C Guo, D Guo, L Fang, T Sang, J Wu, C Guo… - Carbohydrate …, 2021 - Elsevier
This study investigated the effects of water-soluble polysaccharide extracted from the
sporoderm-removed spores of Ganoderma lucidum (GLP) against AOM/DSS-induced …

[HTML][HTML] Reuterin in the healthy gut microbiome suppresses colorectal cancer growth through altering redox balance

HN Bell, RJ Rebernick, J Goyert, R Singhal, M Kuljanin… - Cancer cell, 2022 - cell.com
Microbial dysbiosis is a colorectal cancer (CRC) hallmark and contributes to inflammation,
tumor growth, and therapy response. Gut microbes signal via metabolites, but how the …

[HTML][HTML] Metabolism and colorectal cancer

JC Sedlak, ÖH Yilmaz, J Roper - Annual Review of Pathology …, 2023 - annualreviews.org
Reprogrammed metabolism is a hallmark of colorectal cancer (CRC). CRC cells are geared
toward rapid proliferation, requiring nutrients and the removal of cellular waste in nutrient …

Chemically and biologically engineered bacteria‐based delivery systems for emerging diagnosis and advanced therapy

Z Li, Y Wang, J Liu, P Rawding, J Bu… - Advanced …, 2021 - Wiley Online Library
Bacteria are one of the main groups of organisms, which dynamically and closely participate
in human health and disease development. With the integration of chemical biotechnology …