Exposure to ultraviolet radiation is closely linked to the development of skin cancers in
humans. The ultraviolet B (UVB) radiation wavelength (280–320 nm), in particular, causes …

Human growth hormone (hGH) has emerged as a promising therapeutic agent to prevent
and treat skin photoaging. However, the success of hGH therapy largely lies in the …

Non-melanoma skin cancer is a disease primarily afflicting geriatric patients as evidenced
by the fact that 80% of all non-melanoma skin cancers are diagnosed in patients over the …

The skin harbours transcriptionally and functionally heterogeneous mesenchymal cells that
participate in various physiological activities by secreting biochemical cues. In this study, we …

Canonical ultraviolet (UV) mutation type and spectra are traditionally defined by direct
sequencing-based approaches to map mutations in a limited number of representative DNA …

BACKGROUND: Trichophyton tonsurans is the foremost fungal pathogen of minority
children in the US Despite overwhelming infection rates, it does not appear that this fungus …

Objectives Actinic keratosis have a high risk of progression to a squamous cell carcinoma.
Insulin‐like growth factor 1 and its receptor play a relevant role in restoring repair of …

The activation status of the insulin-like growth factor-1 receptor (IGF-1R) regulates the
cellular response of keratinocytes to ultraviolet B (UVB) exposure, both in vitro and in vivo …

UVB wavelengths of light induce the formation of photoproducts in DNA that are potentially
mutagenic if not properly removed by the nucleotide excision repair machinery. As an …

Abstract Background Ultraviolet-B (UVB) radiation is the leading environmental cause of
skin damage and photoaging. The epidermis and dermis layers of the skin mainly absorb …