Extracellular vesicles (EVs) represent a diverse class of lipid bilayer membrane vesicles
released by both animal and plant cells. These ubiquitous vesicles are involved in …

Purpose Although doxorubicin chemotherapy is commonly applied for treating different
malignant tumors, cardiotoxicity induced by this chemotherapeutic agent restricts its clinical …

Metastasis is the major cause of cancer death, and the development of therapy resistance is
common. The tumor microenvironment can confer chemotherapy resistance …

The notion that stress and cancer are interlinked has dominated lay discourse for decades.
More recent animal studies indicate that stress can substantially facilitate cancer …

Inflammation is an evolutionarily selected defense response to infection or tissue damage
that involves activation and consumption of immune cells in order to reestablish and …

Chemotherapy is a well-known and effective treatment for different cancers; unfortunately, it
has not been as efficient in the eradication of all cancer cells as been expected. The …

Background Although great achievements have been made in the field of cancer therapy,
chemotherapy and radiotherapy remain the mainstay cancer therapeutic modalities …

Cancer is the second cause of death worldwide. Chemotherapy and radiotherapy are the
most common modalities for the treatment of cancer. Experimental studies have shown that …

Background Plant-derived extracellular vesicles (PDEVs) have been exploited for cancer
treatment with several benefits. Bitter melon is cultivated as a vegetable and folk medicine …

Several lines of compelling pre-clinical evidence identify chemotherapy as a potentially
double-edged sword: therapeutic efficacy on the primary tumor may in fact be …