[HTML][HTML] Circulating cell-free nucleic acids: main characteristics and clinical application

M Szilágyi, O Pös, É Márton, G Buglyó… - International journal of …, 2020 - mdpi.com
Liquid biopsy recently became a very promising diagnostic method that has several
advantages over conventional invasive methods. Liquid biopsy may serve as a source of …

miRNAs and ovarian cancer: An overview

B Deb, A Uddin, S Chakraborty - Journal of cellular physiology, 2018 - Wiley Online Library
Ovarian cancer (OC) is the sixth most common cancer in women globally. However, even
with the advances in detection and therapeutics it still represents the most dangerous …

Advances in ovarian cancer treatment beyond PARP inhibitors

F Aliyuda, M Moschetta, A Ghose… - Current Cancer Drug …, 2023 - ingentaconnect.com
Ovarian cancer has become the largest cause of gynaecological cancer-related mortality. It
is typically diagnosed at a late stage and has no effective screening strategy. Ovarian cancer …

[HTML][HTML] Clinical relevance of circulating cell-free microRNAs in ovarian cancer

K Nakamura, K Sawada, A Yoshimura, Y Kinose… - Molecular cancer, 2016 - Springer
Ovarian cancer is the leading cause of death among gynecologic malignancies. Since
ovarian cancer develops asymptomatically, it is often diagnosed at an advanced and …

How ribosomes translate cancer

SO Sulima, IJF Hofman, K De Keersmaecker… - Cancer discovery, 2017 - AACR
A wealth of novel findings, including congenital ribosomal mutations in ribosomopathies and
somatic ribosomal mutations in various cancers, have significantly increased our …

The role of biomarkers in the management of epithelial ovarian cancer

WL Yang, Z Lu, RC Bast Jr - Expert review of molecular diagnostics, 2017 - Taylor & Francis
Introduction: Despite advances in surgery and chemotherapy for ovarian cancer, 70% of
women still succumb to the disease. Biomarkers have contributed to the management of …

[HTML][HTML] MicroRNA let-7g acts as tumor suppressor and predictive biomarker for chemoresistance in human epithelial ovarian cancer

F Biamonte, G Santamaria, A Sacco, FM Perrone… - Scientific reports, 2019 - nature.com
Remarkable deregulation of microRNAs has been demonstrated in epithelial ovarian cancer
(EOC). In particular, some of the let-7 miRNA family members have been proposed as tumor …

[HTML][HTML] Serum exosomal miRNA-145 and miRNA-200c as promising biomarkers for preoperative diagnosis of ovarian carcinomas

S Kim, MC Choi, JY Jeong, S Hwang, SG Jung… - Journal of …, 2019 - ncbi.nlm.nih.gov
Background: Exosomes are extracellular microvesicles that are released by most cells and
widely distributed in various body fluids. Malignant cells secrete large amounts of exosomes …

[HTML][HTML] Drug resistance in ovarian cancer: from mechanism to clinical trial

L Wang, X Wang, X Zhu, L Zhong, Q Jiang, Y Wang… - Molecular Cancer, 2024 - Springer
Ovarian cancer is the leading cause of gynecological cancer-related death. Drug resistance
is the bottleneck in ovarian cancer treatment. The increasing use of novel drugs in clinical …

Development and validation of a microRNA-based signature (MiROvaR) to predict early relapse or progression of epithelial ovarian cancer: a cohort study

M Bagnoli, S Canevari, D Califano, S Losito… - The lancet …, 2016 - thelancet.com
Background Risk of relapse or progression remains high in the treatment of most patients
with epithelial ovarian cancer, and development of a molecular predictor could be a …