[HTML][HTML] Recent developments in receptor tyrosine kinase inhibitors: A promising mainstay in targeted cancer therapy

R Kumar, H Goel, R Solanki, L Rawat… - Medicine in Drug …, 2024 - Elsevier
During the past two decades, significant advances have been made in the discovery and
development of targeted inhibitors aimed at improving the survival rates of cancer patients …

Artificial intelligence assessment of the potential of tocilizumab along with corticosteroids therapy for the management of COVID-19 evoked acute respiratory distress …

C Segú-Vergés, L Artigas, M Coma, RW Peck - Plos one, 2023 - journals.plos.org
Acute respiratory distress syndrome (ARDS), associated with high mortality rate, affects up to
67% of hospitalized COVID-19 patients. Early evidence indicated that the pathogenesis of …

[HTML][HTML] Case report: Pathological complete response to neoadjuvant brigatinib in stage III non-small cell lung cancer with ALK rearrangement

H Seong, SH Kim, MH Kim, JS Cho, A Kim… - Frontiers in …, 2024 - ncbi.nlm.nih.gov
Purpose The use of neoadjuvant anaplastic lymphoma kinase (ALK)-tyrosine kinase
inhibitors (TKIs) has not been extensively explored. The current case report highlights the …

A Systems Biology-and Machine Learning-Based Study to Unravel Potential Therapeutic Mechanisms of Midostaurin as a Multitarget Therapy on FLT3-Mutated AML

M Díaz-Beyá, M García-Fortes, R Valls, L Artigas… - …, 2022 - mdpi.com
Acute myeloid leukemia (AML), a hematologic malignancy that results in bone marrow
failure, is the most common acute leukemia in adults. The presence of FMS-related tyrosine …

[HTML][HTML] Exploring the synergistic effects of cabozantinib and a programmed cell death protein 1 inhibitor in metastatic renal cell carcinoma with machine learning

I Durán, D Castellano, J Puente, L Martín-Couce… - Oncotarget, 2022 - ncbi.nlm.nih.gov
Clinical evidence supports the combination of cabozantinib with an immune checkpoint
inhibitor for the treatment of metastatic clear cell renal cell carcinoma (mccRCC) and …

In silico evaluation of the role of lisdexamfetamine on attention-deficit/hyperactivity disorder common psychiatric comorbidities: mechanistic insights on binge eating …

JR Gutiérrez-Casares, C Segú-Vergés… - Frontiers in …, 2023 - frontiersin.org
Attention-deficit/hyperactivity disorder (ADHD) is a psychiatric condition well recognized in
the pediatric population that can persist into adulthood. The vast majority of patients with …

[HTML][HTML] Urachal inflammatory myofibroblastic tumor with FN1:: ALK fusion: A case report and literature review

N Tara, S Mehta, PP Trivedi, K Patel, T Trivedi - Urology Case Reports, 2024 - Elsevier
Urachal tumors are rare and comprise of both benign and malignant neoplasms. Epithelial
origin tumors are more common than mesenchymal origin tumors. We report a case Urachal …

Diagnostic biomarkers identification of arthritis in Type 2 diabetic patients, using Artificial Intelligence classification techniques applied in Real World Data database …

H Bartra Serrano - 2022 - upcommons.upc.edu
Ddatabases and repositories, including microarray data, are important sources of
information that can be exploited to understand biological processes that in some cases …

[HTML][HTML] Multiplexed detection of predictive fusions and splicing variants in RNA from lung cancer tissue samples using a hybridization-based platform: narrative …

A Giménez-Capitán, C Aguado… - Journal of Xiangya …, 2022 - jxym.amegroups.org
Methods: We performed a search narrative of the scientific literature in PubMed database
and selected all the articles in English from origin until October 5th, 2020 where nCounter …