Advances in the pathogenesis of psoriasis: from keratinocyte perspective
X Zhou, Y Chen, L Cui, Y Shi, C Guo - Cell death & disease, 2022 - nature.com
Psoriasis is a complex long-lasting inflammatory skin disease with high prevalence and
associated comorbidity. It is characterized by epidermal hyperplasia and dermal infiltration …
associated comorbidity. It is characterized by epidermal hyperplasia and dermal infiltration …
Pathogenesis, multi-omics research, and clinical treatment of psoriasis
J Yu, Q Zhao, X Wang, H Zhou, J Hu, L Gu, Y Hu… - Journal of …, 2022 - Elsevier
Psoriasis is a common inflammatory skin disease involving interactions between
keratinocytes and immune cells that significantly affects the quality of life. It is characterized …
keratinocytes and immune cells that significantly affects the quality of life. It is characterized …
MicroRNA-210 overexpression promotes psoriasis-like inflammation by inducing Th1 and Th17 cell differentiation
R Wu, J Zeng, J Yuan, X Deng, Y Huang… - The Journal of …, 2018 - Am Soc Clin Investig
Immune imbalance of T lymphocyte subsets is a hallmark of psoriasis, but the molecular
mechanisms underlying this aspect of psoriasis pathology are poorly understood. Here, we …
mechanisms underlying this aspect of psoriasis pathology are poorly understood. Here, we …
Insights into interplay of immunopathophysiological events and molecular mechanistic cascades in psoriasis and its associated comorbidities
Psoriasis is an inflammatory skin disease with complex pathogenesis and multiple
etiological factors. Besides the essential role of autoreactive T cells and constellation of …
etiological factors. Besides the essential role of autoreactive T cells and constellation of …
Dysregulated epigenetic modifications in psoriasis
C Zeng, LC Tsoi, JE Gudjonsson - Experimental dermatology, 2021 - Wiley Online Library
The observed incidence of psoriasis has been gradually increasing over time (J Am Acad
Dermatol, 03, 2009, 394), but the underlying pathogenic factors have remained unclear …
Dermatol, 03, 2009, 394), but the underlying pathogenic factors have remained unclear …
MiR-223 regulates proliferation and apoptosis of IL-22-stimulated HaCat human keratinocyte cell lines via the PTEN/Akt pathway
R Wang, F Wang, H Cao, J Yang - Life sciences, 2019 - Elsevier
Psoriasis, a chronic inflammatory skin disorder disease, is closely associated with
hyperproliferation of keratinocytes. Upregulated miR-223 has been found in peripheral …
hyperproliferation of keratinocytes. Upregulated miR-223 has been found in peripheral …
Weighted gene coexpression network and experimental analyses identify lncRNA SPRR2C as a regulator of the IL-22-stimulated HaCaT cell phenotype through the …
M Luo, P Huang, Y Pan, Z Zhu, R Zhou, Z Yang… - Cell Death & …, 2021 - nature.com
Psoriasis is a chronic inflammatory disease of the skin with highly complex pathogenesis. In
this study, we identified lncRNA SPRR2C (small proline-rich protein 2C) as a hub gene with …
this study, we identified lncRNA SPRR2C (small proline-rich protein 2C) as a hub gene with …
MicroRNA let-7b inhibits keratinocyte differentiation by targeting IL-6 mediated ERK signaling in psoriasis
Background The extensive involvement of microRNA (miRNA) in the pathophysiology of
psoriasis is well documented. However, in order for this information to be useful in …
psoriasis is well documented. However, in order for this information to be useful in …
Kochia scoparia Saponin Momordin Ic Modulates HaCaT Cell Proliferation and Apoptosis via the Wnt/β‐Catenin Pathway
M Luo, B Zeng, H Wang, Z Yang, Y Peng… - Evidence‐Based …, 2021 - Wiley Online Library
Psoriasis is a chronic, recurrent, immunoinflammatory disease. For a long period, Traditional
Chinese Medicine (TCM) is considered a reliable alternative therapy for patients with …
Chinese Medicine (TCM) is considered a reliable alternative therapy for patients with …
Circ_0060531 knockdown ameliorates IL-22-induced keratinocyte damage by binding to miR-330-5p to decrease GAB1 expression
Q Shi, J Luo, W Chen, Q He, J Long, B Zhang - Autoimmunity, 2022 - Taylor & Francis
Background Psoriasis is a chronic immune-mediated skin disease. Recent studies showed
its pathogenesis involved circular RNA (circRNA). However, the role of circ_0060531 in …
its pathogenesis involved circular RNA (circRNA). However, the role of circ_0060531 in …