Microglia are the resident immune cells of the central nervous system, undertaking
surveillance role and reacting to brain homeostasis and neurological diseases. Recent …

Interictal epileptiform discharges (IEDs), also known as interictal spikes, are large
intermittent electrophysiological events observed between seizures in patients with epilepsy …

During human seizures, organized waves of voltage activity rapidly sweep across the cortex.
Two contradictory theories describe the source of these fast traveling waves: either a slowly …

Objective Stereotactic laser amygdalohippocampotomy (SLAH) is an appealing option for
patients with temporal lobe epilepsy, who often require intracranial monitoring to confirm …

Single-unit recordings performed in temporal lobe epilepsy patients and in models of
temporal lobe seizures have shown that interneurons are active at focal seizure onset. We …

The relationship between clinically accessible epileptic biomarkers and neuronal activity
underlying the transition to seizure is complex, potentially leading to imprecise delineation of …

Loss of consciousness is a hallmark of many epileptic seizures and carries risks of serious
injury and sudden death. While cortical sleep-like activities accompany loss of …

Objective The increased amplitude of ictal activity is a common feature of epileptic seizures,
but the determinants of this amplitude have not been identified. Clinically, ictal amplitudes …

While several studies have attributed the development of tumour-associated seizures to an
excitatory-inhibitory imbalance, we have yet to resolve the spatiotemporal interplay between …

When we see someone's face, our brain usually effortlessly extracts a variety of information
such as facial identity, expression, or gaze direction. While it is widely accepted that …