Connectome-based modelling of neurodegenerative diseases: towards precision medicine and mechanistic insight
JW Vogel, N Corriveau-Lecavalier… - Nature Reviews …, 2023 - nature.com
Neurodegenerative diseases are the most common cause of dementia. Although their
underlying molecular pathologies have been identified, there is substantial heterogeneity in …
underlying molecular pathologies have been identified, there is substantial heterogeneity in …
Mapping neurotransmitter systems to the structural and functional organization of the human neocortex
Neurotransmitter receptors support the propagation of signals in the human brain. How
receptor systems are situated within macro-scale neuroanatomy and how they shape …
receptor systems are situated within macro-scale neuroanatomy and how they shape …
Neuromaps: structural and functional interpretation of brain maps
Imaging technologies are increasingly used to generate high-resolution reference maps of
brain structure and function. Comparing experimentally generated maps to these reference …
brain structure and function. Comparing experimentally generated maps to these reference …
Standardizing workflows in imaging transcriptomics with the abagen toolbox
Gene expression fundamentally shapes the structural and functional architecture of the
human brain. Open-access transcriptomic datasets like the Allen Human Brain Atlas provide …
human brain. Open-access transcriptomic datasets like the Allen Human Brain Atlas provide …
Local molecular and global connectomic contributions to cross-disorder cortical abnormalities
Numerous brain disorders demonstrate structural brain abnormalities, which are thought to
arise from molecular perturbations or connectome miswiring. The unique and shared …
arise from molecular perturbations or connectome miswiring. The unique and shared …
[HTML][HTML] BrainStat: A toolbox for brain-wide statistics and multimodal feature associations
Abstract Analysis and interpretation of neuroimaging datasets has become a
multidisciplinary endeavor, relying not only on statistical methods, but increasingly on …
multidisciplinary endeavor, relying not only on statistical methods, but increasingly on …
Towards a biologically annotated brain connectome
The brain is a network of interleaved neural circuits. In modern connectomics, brain
connectivity is typically encoded as a network of nodes and edges, abstracting away the rich …
connectivity is typically encoded as a network of nodes and edges, abstracting away the rich …
Local structure-function relationships in human brain networks across the lifespan
F Zamani Esfahlani, J Faskowitz, J Slack… - Nature …, 2022 - nature.com
A growing number of studies have used stylized network models of communication to predict
brain function from structure. Most have focused on a small set of models applied globally …
brain function from structure. Most have focused on a small set of models applied globally …
Integrating multimodal and multiscale connectivity blueprints of the human cerebral cortex in health and disease
The brain is composed of disparate neural populations that communicate and interact with
one another. Although fiber bundles, similarities in molecular architecture, and synchronized …
one another. Although fiber bundles, similarities in molecular architecture, and synchronized …