Inflammaging: implications in sarcopenia

E Antuña, C Cachán-Vega, JC Bermejo-Millo… - International Journal of …, 2022 - mdpi.com
In a world in which life expectancy is increasing, understanding and promoting healthy
aging becomes a contemporary demand. In the elderly, a sterile, chronic and low-grade …

Inflammaging: The ground for sarcopenia?

Z Liang, T Zhang, H Liu, Z Li, L Peng, C Wang… - Experimental …, 2022 - Elsevier
Sarcopenia is a progressive skeletal muscle disease that occurs most commonly in the
elderly population, contributing to increased costs and hospitalization. Exercise and …

[HTML][HTML] Long-term human spaceflight and inflammaging: Does it promote aging?

M Capri, M Conte, E Ciurca, C Pirazzini… - Ageing Research …, 2023 - Elsevier
Spaceflight and its associated stressors, such as microgravity, radiation exposure,
confinement, circadian derailment and disruptive workloads represent an unprecedented …

Mitochondrial DNA as inflammatory DAMP: a warning of an aging immune system?

G Zanini, V Selleri, S Lopez Domenech… - Biochemical Society …, 2023 - portlandpress.com
Senescence of the immune system is characterized by a state of chronic, subclinical, low-
grade inflammation termed 'inflammaging', with increased levels of proinflammatory …

Blood biomarkers for sarcopenia: A systematic review and meta-analysis of diagnostic test accuracy studies

R Lian, Q Liu, G Jiang, X Zhang, H Tang, J Lu… - Ageing Research …, 2023 - Elsevier
Biomarkers are emerging as a potential tool for screening or diagnosing sarcopenia. We
aimed to summarize the current evidence on the diagnostic test accuracy of biomarkers for …

Hallmarks of ageing in human skeletal muscle and implications for understanding the pathophysiology of sarcopenia in women and men

A Granic, K Suetterlin, T Shavlakadze… - Clinical …, 2023 - portlandpress.com
Ageing is a complex biological process associated with increased morbidity and mortality.
Nine classic, interdependent hallmarks of ageing have been proposed involving genetic and …

[HTML][HTML] Muscle–Brain crosstalk in cognitive impairment

X Han, M Ashraf, SM Tipparaju… - Frontiers in Aging …, 2023 - ncbi.nlm.nih.gov
Sarcopenia is an age-related, involuntary loss of skeletal muscle mass and strength.
Alzheimer's disease (AD) is the most common cause of dementia in elderly adults. To date …

[HTML][HTML] Diagnostics of inflammaging in relation to sarcopenia

B Morawin, A Tylutka, F Bielewicz… - Frontiers in Public …, 2023 - frontiersin.org
One of the theories about aging focuses on the immune response and relates to the
activation of subclinical and chronic inflammation. This study was designed to investigate …

Association between circulating cell-free mitochondrial DNA and inflammation factors in noninfectious diseases: A systematic review

M Zhou, H Zhang, X Xu, H Chen, B Qi - Plos one, 2024 - journals.plos.org
Objective This study aimed to assess the correlation between the circulating cell-free
mitochondria DNA and inflammation factors in noninfectious disease by meta-analysis of …

The Molecular Mechanisms in Senescent Cells Induced by Natural Aging and Ionizing Radiation

M Ibragimova, A Kussainova, A Aripova, R Bersimbaev… - Cells, 2024 - mdpi.com
This review discusses the relationship between cellular senescence and radiation exposure.
Given the wide range of ionizing radiation sources encountered by people in professional …