Cancer development and its response to therapy are regulated by inflammation, which
either promotes or suppresses tumor progression, potentially displaying opposing effects on …

Inflammation is strictly associated with cancer and plays a key role in tumor development
and progression. Several epidemiological studies have demonstrated that inflammation can …

A Hybrid drug which comprises the incorporation of two drug pharmacophores in one single
molecule are basically designed to interact with multiple targets or to amplify its effect …

Surgery is an important treatment modality for the majority of solid organ cancers.
Unfortunately, cancer recurrence following surgery of curative intent is common, and …

Nitric oxide (NO) and reactive oxygen species exert multiple modulating effects on
inflammation and play a key role in the regulation of immune responses. They affect virtually …

Inflammation is closely linked to cancer, and many anti-cancer agents are also used to treat
inflammatory diseases, such as rheumatoid arthritis. Moreover, chronic inflammation …

Nitric oxide (NO) is a pleiotropic molecule critical to a number of physiological and
pathological processes. The last decade has witnessed major advances in dissecting NO …

Oximes have been studied for decades because of their significant roles as
acetylcholinesterase reactivators. Over the last twenty years, a large number of oximes have …

A series of new hybrids of aspirin (ASA), bearing both nitric oxide (NO) and hydrogen sulfide
(H2S)-releasing moieties were synthesized and designated as NOSH compounds (1–4) …

Cancer metastasis is the spread and growth of tumor cells from the original neoplasm to
further organs. This review analyzes the role of nitric oxide (NO radical dot), a signaling …