A major role for cardiovascular burden in age-related cognitive decline

C Qiu, L Fratiglioni - Nature Reviews Cardiology, 2015 - nature.com
The incidence of dementia and cardiovascular disease (CVD) increases with age. Current
evidence supports the role for both atherosclerosis and arteriosclerosis as a common …

Effects of drinking on late-life brain and cognition

A Topiwala, KP Ebmeier - BMJ Ment Health, 2018 - mentalhealth.bmj.com
Alcohol consumption is common in Western countries and has been increasing in older
adults. Latest figures from Great Britain suggest 75% of those over 65 years drink, an …

Alcohol consumption and risk of dementia: 23 year follow-up of Whitehall II cohort study

S Sabia, A Fayosse, J Dumurgier, A Dugravot… - bmj, 2018 - bmj.com
Objective To examine the association between alcohol consumption and risk of dementia.
Design Prospective cohort study. Setting Civil service departments in London (Whitehall II …

Moderate alcohol consumption as risk factor for adverse brain outcomes and cognitive decline: longitudinal cohort study

A Topiwala, CL Allan, V Valkanova, E Zsoldos… - bmj, 2017 - bmj.com
Objectives To investigate whether moderate alcohol consumption has a favourable or
adverse association or no association with brain structure and function. Design …

Association of low to moderate alcohol drinking with cognitive functions from middle to older age among US adults

R Zhang, L Shen, T Miles, Y Shen, J Cordero… - JAMA network …, 2020 - jamanetwork.com
Importance Studies examining the association of low to moderate drinking with various
cognitive functions have yielded mixed findings. Objective To investigate whether …

Alcohol and aging–an area of increasing concern

AM White, A Orosz, PA Powell, GF Koob - Alcohol, 2023 - Elsevier
Alcohol use is increasing among adults 65 and older and the size of this population is
expanding rapidly. Aging is associated with systemic inflammation, sleep disturbances …

Alcohol use disorders and the brain

R Rao, A Topiwala - Addiction, 2020 - Wiley Online Library
A diagnosis of alcohol use disorder is associated with a higher risk of dementia, but a dose–
response relationship between alcohol intake consumption and cognitive impairment …

Association of healthy lifestyle with cognitive function among Chinese older adults

Z Wang, Y Pang, J Liu, J Wang, Z Xie… - European Journal of …, 2021 - nature.com
Abstract Background/Objectives Dietary patterns and daily life habits have been reported to
be associated with cognitive function in European populations. We aimed to examine the …

Chronic alcohol metabolism results in DNA repair infidelity and cell cycle‐induced senescence in neurons

JKL Sun, D Wu, GCN Wong, TM Lau, M Yang… - Aging cell, 2023 - Wiley Online Library
Chronic binge‐like drinking is a risk factor for age‐related dementia, however, the lasting
and irreversible effect of alcohol on the brain remains elusive. Transcriptomic changes in …

Chronic neurologic effects of alcohol

N Hammoud, J Jimenez-Shahed - Clinics in liver disease, 2019 - liver.theclinics.com
The effects of chronic alcohol abuse on the nervous system span a spectrum of disorders
from acute processes to more chronic, and often irreversible, ones. Such neurologic effects …