Metabolomics for personalized medicine: the input of analytical chemistry from biomarker discovery to point-of-care tests

FA Castelli, G Rosati, C Moguet, C Fuentes… - Analytical and …, 2022 - Springer
Metabolomics refers to the large-scale detection, quantification, and analysis of small
molecules (metabolites) in biological media. Although metabolomics, alone or combined …

[HTML][HTML] Metabolomics and chemometrics: The next-generation analytical toolkit for the evaluation of food quality and authenticity

P Garcia-Perez, PP Becchi, L Zhang… - Trends in Food Science …, 2024 - Elsevier
Background The advances in NMR and mass spectrometry metabolomics allows a
comprehensive profiling of foods, potentially covering geographical origin, authenticity …

[HTML][HTML] Per-and polyfluoroalkyl substance (PFAS) exposure, maternal metabolomic perturbation, and fetal growth in African American women: A meet-in-the-middle …

CJ Chang, DB Barr, PB Ryan, P Panuwet… - Environment …, 2022 - Elsevier
Background Prenatal exposures to per-and polyfluoroalkyl substances (PFAS) have been
linked to reduced fetal growth. However, the detailed molecular mechanisms remain largely …

Negative impacts of nanoplastics on the purification function of submerged plants in constructed wetlands: responses of oxidative stress and metabolic processes

Y Liu, L Wei, H Yu, X Cao, J Peng, H Liu, J Qu - Water Research, 2022 - Elsevier
Constructed wetlands (CWs) are an important barrier to prevent nanoplastics (NPs) and
microplastics (MPs) from entering receiving streams. However, little is known about how the …

[HTML][HTML] The influence of polyphenols on metabolic disorders caused by compounds released from plastics-Review

W Żwierełło, A Maruszewska, M Skórka-Majewicz… - Chemosphere, 2020 - Elsevier
Persistent organic pollutants (POPs) released from plastics into water, soil and air are
significant environmental and health problem. Continuous exposure of humans to these …

Toxicometabolomics: small molecules to answer big toxicological questions

AM Araújo, F Carvalho, P Guedes de Pinho… - Metabolites, 2021 - mdpi.com
Given the high biological impact of classical and emerging toxicants, a sensitive and
comprehensive assessment of the hazards and risks of these substances to organisms is …

automRm: an r package for fully automatic LC-QQQ-MS data preprocessing powered by machine learning

D Eilertz, M Mitterer, JM Buescher - Analytical Chemistry, 2022 - ACS Publications
Preprocessing of liquid chromatography-mass spectrometry (LC-MS) raw data facilitates
downstream statistical and biological data analyses. In the case of targeted LC-MS data …

The study of human serum metabolome on the health effects of glyphosate and early warning of potential damage

QL Zhang, X Liu, MT Gao, X Li, YF Wang, YY Chang… - Chemosphere, 2022 - Elsevier
Glyphosate is one of the most widely used herbicide with high efficiency, low toxicity and
broad-spectrum. In recent decades, increasing evidence suggests that glyphosate may …

Inflammation and cardiometabolic diseases induced by persistent organic pollutants and nutritional interventions: Effects of multi-organ interactions

Z Wang, Y Zhou, X Xiao, A Liu, S Wang… - Environmental …, 2023 - Elsevier
The development and outcome of inflammatory diseases are associated with genetic and
lifestyle factors, which include chemical and nonchemical stressors. Persistent organic …

Metabolomics for exposure assessment and toxicity effects of occupational pollutants: current status and future perspectives

F Dehghani, S Yousefinejad, DI Walker, F Omidi - Metabolomics, 2022 - Springer
Introduction Work-related exposures to harmful agents or factors are associated with an
increase in incidence of occupational diseases. These exposures often represent a complex …