Mitochondria are well known as the centre of energy metabolism in eukaryotic cells.
However, they can not only generate ATP through the tricarboxylic acid cycle and oxidative …

Premature ovarian insufficiency (POI) is a condition that arises from dysfunction or early
depletion of the ovarian follicle pool accompanied by an earlier-than-normal loss of fertility in …

Evidence exists to suggest that ROS induce muscular injury with a subsequent decrease in
physical performance. Supplementation with certain antioxidants is important for physically …

Mitochondria-derived oxidative stress has been implicated in vascular and skeletal muscle
abnormalities in chronic kidney disease (CKD). The purpose of this study was to investigate …

The role of mitochondrial ROS in signalling muscle adaptations to exercise training has not
been explored in detail. We investigated the effect of supplementation with the mitochondria …

The Mitochondria is a critical sub-cellular organelle that plays an integral part in a normal
cellular process. Besides ATP production, the mitochondria participate in various key …

Aim To investigate the effects of mitochondrial‐targeted antioxidants (mitoAOXs) on
glycaemic control, cardiovascular health, and oxidative stress outcomes in humans …

The age-related loss of skeletal muscle mass and physical function leads to a loss of
independence and an increased reliance on health-care. Mitochondria are crucial in the …

Reactive oxygen species (ROS) are oxygen derivatives that arise intrinsically from the
oxidative phosphorylation process and extrinsically as a response to xenobiotics and …

Background Nonalcoholic steatohepatitis (NASH), a severe systemic and inflammatory
subtype of nonsalcoholic fatty liver disease, eventually develops into cirrhosis and …