Diffuse optics for tissue monitoring and tomography

T Durduran, R Choe, WB Baker… - Reports on progress in …, 2010 - iopscience.iop.org
This review describes the diffusion model for light transport in tissues and the medical
applications of diffuse light. Diffuse optics is particularly useful for measurement of tissue …

Wide-field optical mapping of neural activity and brain haemodynamics: considerations and novel approaches

Y Ma, MA Shaik, SH Kim… - … of the Royal …, 2016 - royalsocietypublishing.org
Although modern techniques such as two-photon microscopy can now provide cellular-level
three-dimensional imaging of the intact living brain, the speed and fields of view of these …

Resting-state hemodynamics are spatiotemporally coupled to synchronized and symmetric neural activity in excitatory neurons

Y Ma, MA Shaik, MG Kozberg, SH Kim… - Proceedings of the …, 2016 - National Acad Sciences
Brain hemodynamics serve as a proxy for neural activity in a range of noninvasive
neuroimaging techniques including functional magnetic resonance imaging (fMRI). In …

A quantitative comparison of simultaneous BOLD fMRI and NIRS recordings during functional brain activation

G Strangman, JP Culver, JH Thompson, DA Boas - Neuroimage, 2002 - Elsevier
Near-infrared spectroscopy (NIRS) has been used to noninvasively monitor adult human
brain function in a wide variety of tasks. While rough spatial correspondences with maps …

Diffuse optical imaging of brain activation: approaches to optimizing image sensitivity, resolution, and accuracy

DA Boas, AM Dale, MA Franceschini - Neuroimage, 2004 - Elsevier
Near-infrared spectroscopy (NIRS) and diffuse optical imaging (DOI) are finding widespread
application in the study of human brain activation, motivating further application-specific …

Optical brain imaging in vivo: techniques<?xpp qa?> and applications from animal to man

EMC Hillman - Journal of biomedical optics, 2007 - spiedigitallibrary.org
Optical brain imaging has seen 30 years of intense development, and has grown into a rich
and diverse field. In-vivo imaging using light provides unprecedented sensitivity to functional …

Optical hyperspectral imaging in microscopy and spectroscopy–a review of data acquisition

L Gao, RT Smith - Journal of biophotonics, 2015 - Wiley Online Library
Rather than simply acting as a photographic camera capturing two‐dimensional (x, y)
intensity images or a spectrometer acquiring spectra (λ), a hyperspectral imager measures …

Simultaneous imaging of total cerebral hemoglobin concentration, oxygenation, and blood flow during functional activation

AK Dunn, A Devor, H Bolay, ML Andermann… - Optics letters, 2003 - opg.optica.org
A simple instrument is demonstrated for high-resolution simultaneous imaging of total
hemoglobin concentration and oxygenation and blood flow in the brain by combining rapid …

[PDF][PDF] Coupling of total hemoglobin concentration, oxygenation, and neural activity in rat somatosensory cortex

A Devor, AK Dunn, ML Andermann, I Ulbert, DA Boas… - Neuron, 2003 - cell.com
Recent advances in brain imaging techniques, including functional magnetic resonance
imaging (fMRI), offer great promise for noninvasive mapping of brain function. However, the …

Differences in the hemodynamic response to event-related motor and visual paradigms as measured by near-infrared spectroscopy

G Jasdzewski, G Strangman, J Wagner, KK Kwong… - Neuroimage, 2003 - Elsevier
Several current brain imaging techniques rest on the assumption of a tight coupling between
neural activity and hemodynamic response. The nature of this neurovascular coupling …