Blast-induced traumatic brain injury has been a recent major concern in neurotraumatology.
However, its pathophysiology and mechanism are not understood partly due to insufficient …

Significance: The practicality of optical methods detecting tissue optical contrast (absorption,
elastic and inelastic scattering, fluorescence) for surgical guidance is limited by …

A successful outcome of epilepsy neurosurgery relies on an accurate delineation of the
epileptogenic region to be resected. Functional magnetic resonance imaging (fMRI) would …

Based on enlarged blood oxygen level-dependent (BOLD) responses in cognitively normal
subjects at risk for Alzheimer's disease (AD), compensatory neuronal hyperactivation has …

Observation of brain activities in freely moving animals has become an important approach
for neuroscientists to understand the correlation between brain function and behavior. We …

Assessing intravascular blood oxygen saturation (SO 2) is crucial for characterizing in vivo
microenvironmental changes in preclinical models of injury and disease. However, most …

Our group has already published the possible neuroprotective effect of contralateral forepaw
stimulation in temporary focal ischemia in a study. However, the background is still unclear …

Our perception of the world is represented in widespread, overlapping, and interactive
neuronal networks of the cerebral cortex. A majority of physiological studies on the subject …

The existence of a coupling between changes in neuronal activity, cerebral blood flow and
blood oxygenation is well known. The explicit relationship between these systems, however …

BOLD fMRI localizes activated brain areas by measuring decreases of deoxygenated
hemoglobin (deoxy-Hb) caused by neurovascular coupling. To date, it is unclear whether …