Synthetic agonists of Toll-like receptors 7, 8 and 9
S Agrawal, ER Kandimalla - Biochemical Society Transactions, 2007 - portlandpress.com
TLRs (Toll-like receptors) are a family of innate immune receptors that induce protective
immune responses against infections. Single-stranded viral RNA and bacterial DNA …
immune responses against infections. Single-stranded viral RNA and bacterial DNA …
Engineered nucleic acids encoding a modified erythropoietin and their expression
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Terminally modified RNA
T Chakraborty, S Bancel, SG Hoge, A Roy… - US Patent …, 2017 - Google Patents
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Engineered nucleic acids and methods of use thereof
NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C (= O) C (NC (= O)
C (CCC (N)= O) NC (= O) C (CCC (O)= O) NC (= O) C (C (C) C) NC (= O) C (NC (= O) CN) C …
C (CCC (N)= O) NC (= O) C (CCC (O)= O) NC (= O) C (C (C) C) NC (= O) C (NC (= O) CN) C …
Modified polynucleotides for the production of biologics and proteins associated with human disease
S Bancel, T Chakraborty, A De Fougerolles… - US Patent …, 2015 - Google Patents
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Modified polynucleotides for the production of secreted proteins
T Chakraborty, A De Fougerolles - US Patent 9,192,651, 2015 - Google Patents
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In vivo production of proteins
S Bancel, T Chakraborty, A De Fougerolles… - US Patent …, 2015 - Google Patents
2013-03-19 Assigned to modeRNA Therapeutics reassignment modeRNA Therapeutics
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …
Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
T Chakraborty, A De Fougerolles - US Patent 9,303,079, 2016 - Google Patents
2013-03-19 Assigned to modeRNA Therapeutics reassignment modeRNA Therapeutics
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …
Engineered nucleic acids and methods of use thereof
S Bancel, JP Schrum, A Aristarkhov - US Patent 9,464,124, 2016 - Google Patents
A61K48/0075—Medicinal preparations containing genetic material which is inserted into
cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of …
cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of …
Compositions and methods of altering cholesterol levels
SG Hoge, A De Fougerolles, JL Ellsworth - US Patent 8,980,864, 2015 - Google Patents
2014-03-21 Assigned to MODERNA THERAPEUTICS, INC. reassignment MODERNA
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