Interactions between obesity and obstructive sleep apnea: implications for treatment

A Romero-Corral, SM Caples, F Lopez-Jimenez… - Chest, 2010 - Elsevier
Obstructive sleep apnea (OSA) adversely affects multiple organs and systems, with
particular relevance to cardiovascular disease. Several conditions associated with OSA …

Sleep apnea and cardiovascular disease: An American heart association/American college of cardiology foundation scientific statement from the American heart …

VK Somers, DP White, R Amin, WT Abraham, F Costa… - Circulation, 2008 - Am Heart Assoc
Experimental approaches directed at addressing these issues are limited by several
considerations. First, the close association between obesity and OSA often obscures …

Effects of poor and short sleep on glucose metabolism and obesity risk

K Spiegel, E Tasali, R Leproult… - Nature Reviews …, 2009 - nature.com
The importance of sleep to hormones and glucose metabolism was first documented more
than four decades ago. Since then, sleep curtailment has become an endemic behavior in …

Sleep loss: a novel risk factor for insulin resistance and Type 2 diabetes

K Spiegel, K Knutson, R Leproult… - Journal of applied …, 2005 - journals.physiology.org
Chronic sleep loss as a consequence of voluntary bedtime restriction is an endemic
condition in modern society. Although sleep exerts marked modulatory effects on glucose …

Role of sleep quality in the metabolic syndrome

D Koren, M Dumin, D Gozal - Diabetes, metabolic syndrome and …, 2016 - Taylor & Francis
Emerging evidence has assigned an important role to sleep as a modulator of metabolic
homeostasis. The impact of variations in sleep duration, sleep-disordered breathing, and …

Sleep apnoea as an independent risk factor for cardiovascular disease: current evidence, basic mechanisms and research priorities

WT McNicholas, MR Bonsignore… - European …, 2007 - Eur Respiratory Soc
Considerable evidence is available in support of an independent association between
obstructive sleep apnoea syndrome (OSAS) and cardiovascular disease, which is …

Sleep duration and diabetes risk: population trends and potential mechanisms

MA Grandner, A Seixas, S Shetty, S Shenoy - Current diabetes reports, 2016 - Springer
Sleep is important for regulating many physiologic functions that relate to metabolism.
Because of this, there is substantial evidence to suggest that sleep habits and sleep …

Impact of untreated obstructive sleep apnea on glucose control in type 2 diabetes

RS Aronsohn, H Whitmore, E Van Cauter… - American journal of …, 2010 - atsjournals.org
Rationale: Obstructive sleep apnea (OSA), a treatable sleep disorder that is associated with
alterations in glucose metabolism in individuals without diabetes, is a highly prevalent …

Frequent occurrence of hypogonadotropic hypogonadism in type 2 diabetes

S Dhindsa, S Prabhakar, M Sethi… - The Journal of …, 2004 - academic.oup.com
Type 2 diabetes is associated with lower total testosterone (T) levels in cross-sectional
studies. However, it is not known whether the defect is primary or secondary. We …

Obstructive sleep apnea as a risk factor for type 2 diabetes

N Botros, J Concato, V Mohsenin, B Selim… - The American journal of …, 2009 - Elsevier
PURPOSE: Cross-sectional studies have documented the co-occurrence of obstructive
sleep apnea (hereafter, sleep apnea) with glucose intolerance, insulin resistance, and type …