[HTML][HTML] The role of oxidative stress in atherosclerosis

M Batty, MR Bennett, E Yu - Cells, 2022 - mdpi.com
Atherosclerosis is a chronic inflammatory disease of the vascular system and is the leading
cause of cardiovascular diseases worldwide. Excessive generation of reactive oxygen …

[HTML][HTML] An overview of the cardiorenal protective mechanisms of SGLT2 inhibitors

T Salvatore, R Galiero, A Caturano, L Rinaldi… - International Journal of …, 2022 - mdpi.com
Sodium-glucose co-transporter 2 (SGLT2) inhibitors block glucose reabsorption in the renal
proximal tubule, an insulin-independent mechanism that plays a critical role in glycemic …

[HTML][HTML] Uric acid and oxidative stress—relationship with cardiovascular, metabolic, and renal impairment

ME Gherghina, I Peride, M Tiglis, TP Neagu… - International Journal of …, 2022 - mdpi.com
Background: The connection between uric acid (UA) and renal impairment is well known
due to the urate capacity to precipitate within the tubules or extra-renal system. Emerging …

Uric acid in metabolic syndrome: does uric acid have a definitive role?

S Copur, A Demiray, M Kanbay - European journal of internal medicine, 2022 - Elsevier
Increased serum uric acid (SUA) levels are commonly seen in patients with metabolic
syndrome and are widely accepted as risk factors for hypertension, gout, non-alcoholic fatty …

[HTML][HTML] Atherosclerosis and inflammation: Insights from the theory of general pathological processes

E Gusev, A Sarapultsev - International Journal of Molecular Sciences, 2023 - mdpi.com
Recent advances have greatly improved our understanding of the molecular mechanisms
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …

[HTML][HTML] Caffeine and its antioxidant properties—it is all about dose and source

BE Ősz, G Jîtcă, RE Ștefănescu, A Pușcaș… - International journal of …, 2022 - mdpi.com
Caffeine is the most frequently used substance with a central nervous system stimulant
effect, but its consumption is most often due to the intake of foods and drinks that contain it …

[HTML][HTML] Novel insights into the molecular mechanisms of atherosclerosis

A Wojtasińska, W Frąk, W Lisińska, N Sapeda… - International Journal of …, 2023 - mdpi.com
Atherosclerosis is one of the most fatal diseases in the world. The associated thickening of
the arterial wall and its background and consequences make it a very composite disease …

Serum uric acid lowering and effects of sodium‐glucose cotransporter‐2 inhibitors on gout: A meta‐analysis and meta‐regression of randomized controlled trials

M Banerjee, R Pal, I Maisnam… - Diabetes, Obesity …, 2023 - Wiley Online Library
Aims To pool the effects of sodium‐glucose cotransporter‐2 (SGLT2) inhibitors on gout and
to investigate the association of these effects with baseline serum uric acid (SUA), SUA …

[HTML][HTML] Targeting oxidative stress as a preventive and therapeutic approach for cardiovascular disease

Q Yan, S Liu, Y Sun, C Chen, S Yang, M Lin… - Journal of Translational …, 2023 - Springer
Cardiovascular diseases (CVDs) continue to exert a significant impact on global mortality
rates, encompassing conditions like pulmonary arterial hypertension (PAH), atherosclerosis …

[HTML][HTML] Anti-inflammatory therapeutic mechanisms of natural products: Insight from rosemary diterpenes, carnosic acid and carnosol

S Habtemariam - Biomedicines, 2023 - mdpi.com
Carnosic acid (CA) and carnosol (CAR) are two major diterpenes of the rosemary plant
(Rosmarinus officinalis). They possess a phenolic structural moiety and are endowed with …