Abstract Type 2 diabetes (T2D), which has currently become a global pandemic, is a
metabolic disease largely characterised by impaired insulin secretion and action. Significant …

Diabetes mellitus (DM) is a metabolic disorder that occurs in the body because of decreased
insulin activity and/or insulin secretion. Pathological changes such as nephropathy …

The pathogenesis and clinical features of diabetic cardiomyopathy have been well-studied
in the past decade, but effective approaches to prevent and treat this disease are limited …

Diabetes mellitus, a very common and multifaceted metabolic disorder is considered as one
of the fastest growing public health problems in the world. It is characterized by …

G protein-coupled receptors (GPCRs) are the most intensively studied drug targets, mostly
due to their substantial involvement in human pathophysiology and their pharmacological …

Type 2 diabetes mellitus (T2DM) is the most widespread form of diabetes, characterized by
chronic hyperglycaemia, insulin resistance, and inefficient insulin secretion and action …

Renin-angiotensin-aldosterone system (RAAS) is a vital system of human body, as it
maintains plasma sodium concentration, arterial blood pressure and extracellular volume …

Diabetes mellitus is seen to be prevalent among the different epidemics. The prevalence
rate of the diabetes mellitus is seen to be increasing in different regions of the world. Type 2 …

Neutrophils are primary effector cells of innate immunity and fight infection by phagocytosis
and degranulation. Activated neutrophils also release neutrophil extracellular traps (NETs) …

Nitric oxide (NO) represents a potential wound therapeutic agent due to its ability to regulate
inflammation and eradicate bacterial infections. Two broad strategies exist to utilize NO for …