[HTML][HTML] DNA methylation-based diagnostic, prognostic, and predictive biomarkers in colorectal cancer
DNA methylation is an epigenetic mechanism regulating gene expression. Changes in DNA
methylation were suggested to be useful biomarkers for diagnosis, and for the determination …
methylation were suggested to be useful biomarkers for diagnosis, and for the determination …
Liquid biopsies based on DNA methylation as biomarkers for the detection and prognosis of lung cancer
P Li, S Liu, L Du, G Mohseni, Y Zhang, C Wang - Clinical epigenetics, 2022 - Springer
Lung cancer (LC) is the main cause of cancer-related mortality. Most LC patients are
diagnosed in an advanced stage when the symptoms are obvious, and the prognosis is …
diagnosed in an advanced stage when the symptoms are obvious, and the prognosis is …
Advancements in mri-based radiomics and artificial intelligence for prostate cancer: A comprehensive review and future prospects
Simple Summary The integration of artificial intelligence (AI) into radiomic models has
become increasingly popular due to advances in computer-aided diagnosis tools. These …
become increasingly popular due to advances in computer-aided diagnosis tools. These …
The importance of metabolic and environmental factors in the occurrence of oxidative stress during pregnancy
MZ Jovandaric, S Babic, M Raus, B Medjo - International Journal of …, 2023 - mdpi.com
Metabolic changes in pregnant women begin in the first weeks after conception under the
influence of placental hormones that affect the metabolism of all nutrients. An increased …
influence of placental hormones that affect the metabolism of all nutrients. An increased …
From omics to multi-omics approaches for in-depth analysis of the molecular mechanisms of prostate cancer
E Nevedomskaya, B Haendler - International Journal of Molecular …, 2022 - mdpi.com
Cancer arises following alterations at different cellular levels, including genetic and
epigenetic modifications, transcription and translation dysregulation, as well as metabolic …
epigenetic modifications, transcription and translation dysregulation, as well as metabolic …
[HTML][HTML] Omics technologies to understand drug toxicity mechanisms
N Nguyen, D Jennen, J Kleinjans - Drug Discovery Today, 2022 - Elsevier
Highlights•High throughput technologies (HTPs) provide quantitative and multi-dimensional
omics data.•Available HTPs can capture biological alterations in DNA, RNA, protein, and …
omics data.•Available HTPs can capture biological alterations in DNA, RNA, protein, and …
[HTML][HTML] Paternal combined botanicals contribute to the prevention of estrogen receptor–negative mammary Cancer in transgenic mice
Background Parental nutritional interventions have considerably affected gametogenesis
and embryogenesis, leading to the differential susceptibility of offspring to chronic diseases …
and embryogenesis, leading to the differential susceptibility of offspring to chronic diseases …
Dietary impacts on gestational diabetes: connection between gut microbiome and epigenetic mechanisms
T Bankole, H Winn, Y Li - Nutrients, 2022 - mdpi.com
Gestational diabetes mellitus (GDM) is one of the most common obstetric complications due
to an increased level of glucose intolerance during pregnancy. The prevalence of GDM …
to an increased level of glucose intolerance during pregnancy. The prevalence of GDM …
Introduction to epigenetics
Epigenetics is the study of inherited variations in gene expression that do not involve
changes to DNA sequences. Over 200 unique cell types in a human adult have a nearly …
changes to DNA sequences. Over 200 unique cell types in a human adult have a nearly …
Epigenomic characterization of lymphoid neoplasms
M Duran-Ferrer, JI Martín-Subero - Annual Review of Pathology …, 2024 - annualreviews.org
Lymphoid neoplasms represent a heterogeneous group of disease entities and subtypes
with markedly different molecular and clinical features. Beyond genetic alterations, lymphoid …
with markedly different molecular and clinical features. Beyond genetic alterations, lymphoid …