[HTML][HTML] DNA methylation-based diagnostic, prognostic, and predictive biomarkers in colorectal cancer

D Müller, B Győrffy - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2022 - Elsevier
DNA methylation is an epigenetic mechanism regulating gene expression. Changes in DNA
methylation were suggested to be useful biomarkers for diagnosis, and for the determination …

Liquid biopsies based on DNA methylation as biomarkers for the detection and prognosis of lung cancer

P Li, S Liu, L Du, G Mohseni, Y Zhang, C Wang - Clinical epigenetics, 2022 - Springer
Lung cancer (LC) is the main cause of cancer-related mortality. Most LC patients are
diagnosed in an advanced stage when the symptoms are obvious, and the prognosis is …

Advancements in mri-based radiomics and artificial intelligence for prostate cancer: A comprehensive review and future prospects

A Chaddad, G Tan, X Liang, L Hassan, S Rathore… - Cancers, 2023 - mdpi.com
Simple Summary The integration of artificial intelligence (AI) into radiomic models has
become increasingly popular due to advances in computer-aided diagnosis tools. These …

The importance of metabolic and environmental factors in the occurrence of oxidative stress during pregnancy

MZ Jovandaric, S Babic, M Raus, B Medjo - International Journal of …, 2023 - mdpi.com
Metabolic changes in pregnant women begin in the first weeks after conception under the
influence of placental hormones that affect the metabolism of all nutrients. An increased …

From omics to multi-omics approaches for in-depth analysis of the molecular mechanisms of prostate cancer

E Nevedomskaya, B Haendler - International Journal of Molecular …, 2022 - mdpi.com
Cancer arises following alterations at different cellular levels, including genetic and
epigenetic modifications, transcription and translation dysregulation, as well as metabolic …

[HTML][HTML] Omics technologies to understand drug toxicity mechanisms

N Nguyen, D Jennen, J Kleinjans - Drug Discovery Today, 2022 - Elsevier
Highlights•High throughput technologies (HTPs) provide quantitative and multi-dimensional
omics data.•Available HTPs can capture biological alterations in DNA, RNA, protein, and …

[HTML][HTML] Paternal combined botanicals contribute to the prevention of estrogen receptor–negative mammary Cancer in transgenic mice

S Li, H Wu, M Chen, TO Tollefsbol - The Journal of Nutrition, 2023 - Elsevier
Background Parental nutritional interventions have considerably affected gametogenesis
and embryogenesis, leading to the differential susceptibility of offspring to chronic diseases …

Dietary impacts on gestational diabetes: connection between gut microbiome and epigenetic mechanisms

T Bankole, H Winn, Y Li - Nutrients, 2022 - mdpi.com
Gestational diabetes mellitus (GDM) is one of the most common obstetric complications due
to an increased level of glucose intolerance during pregnancy. The prevalence of GDM …

Introduction to epigenetics

N Singla, R Thapa, R Kulshrestha, AA Bhat… - Targeting epigenetics in …, 2023 - Springer
Epigenetics is the study of inherited variations in gene expression that do not involve
changes to DNA sequences. Over 200 unique cell types in a human adult have a nearly …

Epigenomic characterization of lymphoid neoplasms

M Duran-Ferrer, JI Martín-Subero - Annual Review of Pathology …, 2024 - annualreviews.org
Lymphoid neoplasms represent a heterogeneous group of disease entities and subtypes
with markedly different molecular and clinical features. Beyond genetic alterations, lymphoid …