Capillary electrophoresis separations of glycans

G Lu, CL Crihfield, S Gattu, LM Veltri… - Chemical …, 2018 - ACS Publications
Capillary electrophoresis has emerged as a powerful approach for carbohydrate analyses
since 2014. The method provides high resolution capable of separating carbohydrates by …

Glycan-based biomarkers for diagnosis of cancers and other diseases: Past, present, and future

M Hu, Y Lan, A Lu, X Ma, L Zhang - Progress in Molecular Biology and …, 2019 - Elsevier
Glycans are essential biomolecules in regulating human physiology and pathology ranging
from signal transduction to microbial infections. Developing complex human diseases, such …

The functional roles of protein glycosylation in human maternal–fetal crosstalk

J Zhong, J Li, GJ Burton, H Koistinen… - Human …, 2024 - academic.oup.com
BACKGROUND The establishment of maternal–fetal crosstalk is vital to a successful
pregnancy. Glycosylation is a post-translational modification in which glycans …

Roles of N-linked glycosylation and glycan-binding proteins in placentation: trophoblast infiltration, immunomodulation, angiogenesis, and pathophysiology

Z Huang, PF Lai, ATH Cocker… - Biochemical Society …, 2023 - portlandpress.com
Protein N-linked glycosylation is a structurally diverse post-translational modification that
stores biological information in a larger order of magnitude than other post-translational …

Human trophoblast requires galectin-3 for cell migration and invasion

Ž Bojić-Trbojević, M Jovanović Krivokuća, A Vilotić… - Scientific reports, 2019 - nature.com
Invasive extravillous cytotrophoblast of the human placenta expresses galectins-1,-3, and-8
in vivo and in vitro. This study aimed to investigate the potential role of galectin-3 in cell …

Glycosylation and aging

A Cindrić, J Krištić, M Martinić Kavur… - The Role of Glycosylation …, 2021 - Springer
Human lifespan has increased significantly in the last 200 years, emphasizing our need to
age healthily. Insights into molecular mechanisms of aging might allow us to slow down its …

Tracking nutrient transfer at the human maternofetal interface from 4 weeks to term

CJP Jones, RH Choudhury, JD Aplin - Placenta, 2015 - Elsevier
Introduction In this study we have tracked glycogen and glycoprotein flux associated with
nutrient uptake into trophoblast in early deciduochorial and later haemochorial placenta …

N- and O-glycan cell surface protein modifications associated with cellular senescence and human aging

Y Itakura, N Sasaki, D Kami, S Gojo, A Umezawa… - Cell & bioscience, 2016 - Springer
Background Glycans play essential roles in biological functions such as differentiation and
cancer. Recently, glycans have been considered as biomarkers for physiological aging …

[HTML][HTML] Serum glycoprotein-derived N-and O-linked glycans as cancer biomarkers

Y Lan, C Hao, X Zeng, Y He, P Zeng… - American journal of …, 2016 - ncbi.nlm.nih.gov
Early detection of cancer is the key to improving survival. Since most clinically used serum
cancer biomarkers are either glycoproteins or glycan structures that can be recognized by …

Altered β1, 6-GlcNAc and bisecting GlcNAc-branched N-glycan on integrin β1 are associated with early spontaneous miscarriage in humans

M Zhang, M Wang, R Gao, X Liu, X Chen… - Human …, 2015 - academic.oup.com
Abstract STUDY QUESTION Do N-acetylglucosaminyltransferase (GnT-V) and N-
acetylglucosaminyltransferase III (GnT-III) play an important role in early spontaneous …