Growth hormone in fertility and infertility: Mechanisms of action and clinical applications
CW Chang, YW Sung, YW Hsueh, YY Chen… - Frontiers in …, 2022 - frontiersin.org
Secreted by the anterior pituitary gland, growth hormone (GH) is a peptide that plays a
critical role in regulating cell growth, development, and metabolism in multiple targeted …
critical role in regulating cell growth, development, and metabolism in multiple targeted …
The clinical application of growth hormone and its biological and molecular mechanisms in assisted reproduction
P Pan, X Huang - International Journal of Molecular Sciences, 2022 - mdpi.com
Growth hormone (GH) has been used as a co-gonadotrophin in assisted reproduction,
particularly in poor ovarian responders. The application of GH has been alleged to activate …
particularly in poor ovarian responders. The application of GH has been alleged to activate …
Importance of IGF-I levels in IVF: potential relevance for growth hormone (GH) supplementation
N Gleicher, SK Darmon, E Molinari, P Patrizio… - Journal of assisted …, 2022 - Springer
Purpose Growth hormone (GH) supplementation in association with in vitro fertilization (IVF)
is worldwide again increasing, even though study outcomes have been discrepant. Since …
is worldwide again increasing, even though study outcomes have been discrepant. Since …
Preclinical evaluation of the ROCK1 inhibitor, GSK269962A, in acute myeloid leukemia
T Pan, S Wang, H Feng, J Xu, M Zhang… - Frontiers in …, 2022 - frontiersin.org
Acute myeloid leukemia (AML) is an aggressive hematologic malignancy with high mortality
that urgently requires new treatments. ROCK1 plays an essential role in regulating growth …
that urgently requires new treatments. ROCK1 plays an essential role in regulating growth …
The effect of growth hormone adjuvant therapy on assisted reproductive technologies outcomes in patients with diminished ovarian reserve or poor ovarian response
Low response of patients with diminished ovarian reserve to exogenous gonadotropins in
controlled ovarian stimulation (COS) protocols is one of the important problems of …
controlled ovarian stimulation (COS) protocols is one of the important problems of …
Comparative efficacy of different growth hormone supplementation protocols in improving clinical outcomes in women with poor ovarian response undergoing …
Z Xu, W Tong, Z Yang, H Zhang, X Chen - Scientific Reports, 2024 - nature.com
Growth hormone (GH) has a long-standing history of use as an adjunctive therapy in the
treatment of poor ovarian response (POR), but the optimal dosage and timing remains …
treatment of poor ovarian response (POR), but the optimal dosage and timing remains …
Effect of growth hormone cotreatment in sub-fertile women≥ 40 years: a meta-analysis
M Elkalyoubi, L Schindler… - Reproduction and Fertility, 2023 - raf.bioscientifica.com
Treatment of sub-fertile women aged≥ 40 years old (advanced maternal age (AMA)) is
challenging. Co-treatment with growth hormone (GH) is suggested to improve reproductive …
challenging. Co-treatment with growth hormone (GH) is suggested to improve reproductive …
Human growth hormone use in poor ovarian response–caution and opportunities
Human growth hormone has found favour as a co-gonadotrophin in assisted reproduction
particularly in the circumstances of a poor response to stimulation. Its use has been based …
particularly in the circumstances of a poor response to stimulation. Its use has been based …
Supplementation of the in vitro maturation culture medium of mouse oocytes with growth hormone improves pregnancy outcomes
This study aimed to examine the effects of adding growth hormone (GH) into the in vitro
maturation (IVM) culture medium of mouse oocytes on pregnancy outcomes. Cumulus …
maturation (IVM) culture medium of mouse oocytes on pregnancy outcomes. Cumulus …
The effect of human growth hormone on endometrial growth in controlled ovarian hyperstimulation cycles
B Bavan, RM Gardner, WY Zhang… - Journal of Personalized …, 2022 - mdpi.com
This study aims to compare endometrial growth before and after the addition of human
growth hormone (hGH) in controlled ovarian hyperstimulation (COH) cycles. A 5-year …
growth hormone (hGH) in controlled ovarian hyperstimulation (COH) cycles. A 5-year …