Strategies for increasing pancreatic tumor immunogenicity
BA Johnson III, M Yarchoan, V Lee, DA Laheru… - Clinical Cancer …, 2017 - AACR
Immunotherapy has changed the standard of care for multiple deadly cancers, including
lung, head and neck, gastric, and some colorectal cancers. However, single-agent …
lung, head and neck, gastric, and some colorectal cancers. However, single-agent …
DNA vaccines to attack cancer: Strategies for improving immunogenicity and efficacy
A Tiptiri-Kourpeti, K Spyridopoulou, A Pappa… - Pharmacology & …, 2016 - Elsevier
DNA vaccination represents a smart and promising approach to cancer immunotherapy.
DNA vaccines for cancer immunotherapy are designed to deliver one or several genes …
DNA vaccines for cancer immunotherapy are designed to deliver one or several genes …
Vaccination with poly (IC: LC) and peptide-pulsed autologous dendritic cells in patients with pancreatic cancer
S Mehrotra, CD Britten, S Chin, E Garrett-Mayer… - Journal of hematology & …, 2017 - Springer
Abstract Background Dendritic cells (DCs) enhance the quality of anti-tumor immune
response in patients with cancer. Thus, we posit that DC-based immunotherapy, in …
response in patients with cancer. Thus, we posit that DC-based immunotherapy, in …
Multicenter phase I trial of a DNA vaccine encoding the androgen receptor ligand-binding domain (pTVG-AR, MVI-118) in patients with metastatic prostate cancer
CE Kyriakopoulos, JC Eickhoff, AC Ferrari… - Clinical Cancer …, 2020 - AACR
Purpose: Preclinical studies demonstrated that a DNA vaccine (pTVG-AR, MVI-118)
encoding the androgen receptor ligand-binding domain (AR LBD) augmented antigen …
encoding the androgen receptor ligand-binding domain (AR LBD) augmented antigen …
Vaccines based on whole recombinant Saccharomyces cerevisiae cells
A Ardiani, JP Higgins, JW Hodge - FEMS yeast research, 2010 - academic.oup.com
The ultimate goal of therapeutic vaccines is to activate and exploit the patient's own immune
system to vigorously and dynamically seek and eradicate established malignant or virally …
system to vigorously and dynamically seek and eradicate established malignant or virally …
Potential targets for pancreatic cancer immunotherapeutics
LF Dodson, WG Hawkins, P Goedegebuure - Immunotherapy, 2011 - Taylor & Francis
Pancreatic adenocarcinoma is the fourth leading cause of cancer death with an overall 5-
year survival of less than 5%. As there is ample evidence that pancreatic adenocarcinomas …
year survival of less than 5%. As there is ample evidence that pancreatic adenocarcinomas …
Listeria attenuated for entry into non-phagocytic cells, vaccines comprising the Listeria, and methods of use thereof
TW Dubensky Jr, DG Brockstedt, DN Cook - US Patent 7,691,393, 2010 - Google Patents
US7691393B2 - Listeria attenuated for entry into non-phagocytic cells, vaccines comprising
the Listeria, and methods of use thereof - Google Patents US7691393B2 - Listeria …
the Listeria, and methods of use thereof - Google Patents US7691393B2 - Listeria …
Expression of a natural tumor antigen by thymic epithelial cells impairs the tumor-protective CD4+ T-cell repertoire
R Bos, S Van Duikeren, T Van Hall, P Kaaijk, R Taubert… - Cancer research, 2005 - AACR
A variety of antigens that display a highly tissue-specific expression pattern have recently
found to be also expressed in medullary thymic epithelial cells (mTEC). This unique feature …
found to be also expressed in medullary thymic epithelial cells (mTEC). This unique feature …
Recombinant nucleic acid molecules, expression cassettes, and bacteria, and methods of use thereof
TW Dubensky Jr, DA Portnoy, WS Luckett… - US Patent …, 2010 - Google Patents
2005-06-20 Assigned to CERUS CORPORATION reassignment CERUS CORPORATION
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …
The androgen receptor: a biologically relevant vaccine target for the treatment of prostate cancer
BM Olson, LE Johnson, DG McNeel - Cancer Immunology …, 2013 - Springer
The androgen receptor (AR) plays an essential role in the development and progression of
prostate cancer. However, while it has long been the primary molecular target of metastatic …
prostate cancer. However, while it has long been the primary molecular target of metastatic …