Kidney disease associated with chronic cadmium (Cd) exposure is primarily due to proximal
tubule cell damage. This results in a sustained decline in glomerular filtration rate (GFR) and …

Acute kidney injury (AKI), characterized by acute renal dysfunction, is an increasingly
common clinical problem and an important risk factor in the subsequent development of …

Despite the increasing incidence of kidney-related diseases, we are still far from
understanding the underlying mechanisms of these diseases and their progression. This …

Chronic glomerular and tubular nephrotoxicity is reported in 20–50% and 20–25%,
respectively, of children and adolescents treated with ifosfamide and 60–80% and 10–30 …

Epigenetic memory, which refers to the ability of cells to retain and transmit epigenetic marks
to their daughter cells, maintains unique gene expression patterns. Establishing …

Chronic kidney disease (CKD) is characterized by a gradual loss of kidney function and
affects~ 13.4% of the global population. Progressive tubulointerstitial fibrosis, driven in part …

SGLT2 inhibitor-related nephroprotection is—at least partially—mediated by anti-
inflammatory drug effects, as previously demonstrated in diabetic animal and human …

Chronic kidney disease (CKD) is associated to an increased risk of death, CKD progression,
and acute kidney injury (AKI) even from early stages, when glomerular filtration rate (GFR) is …

Precise coupling between cellular physiology and metabolism is emerging as a vital
relationship underpinning tissue health and longevity. Nevertheless, functional-metabolic …

Chronic kidney disease (CKD) is a major healthcare issue worldwide. However, the
prevalence of pediatric CKD has never been systematically assessed and consistent …