Recent evidence suggests that injury to the renal vasculature may play an important role in
the pathogenesis of both early and chronic ischemic acute kidney injury (AKI). Established …

It is hypothesized that rarefaction of peritubular capillaries represents a critical event,
following ischemic injury, that permanently alters renal function and predisposes patients to …

First published August 9, 2001; 10.1152/ajprenal. 00050.2001.—Acute episodes of severe
renal ischemia result in acute renal failure (ARF). These episodes are followed by a …

Early medullary hypoxic injury from radiocontrast and indomethacin. We evaluated the acute
changes in cortical and outer medullary oxygen tension and the alterations in renal function …

In contrast to apoptosis and autophagy, necrotic cell death was considered to be a random,
passive cell death without definable mediators. However, this dogma has been challenged …

A classic nephrology reference for over 20 years, Seldin & Giebisch's The Kidney, is the
acknowledged authority on renal physiology and pathophysiology. The fourth edition follows …

It is now becoming apparent that the medullary circulation in the kidney can be regulated
separately from overall renal blood flow. This characteristic of the medullary circulation plays …

Red cell trapping and postischemic renal blood flow. Differences between the cortex, outer
and inner medulla. The distribution of blood flow in the rat kidney after 60 minutes of renal …

Tp53-induced glycolysis and apoptosis regulator (TIGAR) activation blocks glycolytic ATP
synthesis by inhibiting phosphofructokinase-1 activity. Our data indicate that TIGAR is …

Red cell trapping after ischemia and long-term kidney damage. Influence of hematocrit. The
influence of the hematocrit (Hct) on the trapping of red blood cells (RBC) in the renal …