Gallic acid (GA), also known as 3, 4, 5-trihydroxybenzoic acid, is a natural secondary
metabolite and widely isolated from various fruits, plants and nuts. In recent years, GA has …

Fatty liver diseases, which are commonly associated with high-fat/calorie diet, heavy alcohol
consumption and/or other metabolic disorder causes, lead to serious medical concerns …

Diabetes mellitus (DM) is a major world health problem and one of the most studied
diseases, which are highly prevalent in the whole world, it is frequently associated with …

Inflammation is the principal response invoked by the body to address injuries. Despite
inflammation constituting a crucial component of tissue repair, it is well known that …

Neurodegenerative diseases are characterized by the progressive functional loss of
neurons in the brain, causing cognitive impairment and motoneuron disability. Although …

Many natural products present in our diet, including flavonoids, can prevent the progression
of cancer and other diseases. Resveratrol, a natural polyphenol present in various fruits and …

Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease and
represents the hepatic expression of several metabolic abnormalities of high epidemiologic …

Few medications are available for meeting the increasing disease burden of nonalcoholic
fatty liver disease (NAFLD) and its progressive stage, nonalcoholic steatohepatitis (NASH) …

Ethnopharmacological relevance Plants are a natural treasure trove; their secondary
metabolites participate in several pharmacological processes, making them a crucial …

Background Studies have demonstrated that resveratrol (a natural polyphenol) and caloric
restriction activate Sirtuin-1 (SIRT1) and induce autophagy. Furthermore, autophagy is …