Losartan is an angiotensin II receptor blocker (ARB) that impedes transforming growth factor
(TGF) beta signaling by inhibiting activation of signal transduction molecule extracellular …

Allogeneic hematopoietic stem cell transplantation is a definitive therapy for a variety of
disorders. One of the complications is acute graft-versus-host disease (aGVHD), which has a …

Ocular graft-versus-host-disease (GVHD) remains a significant clinical complication after
allogeneic hematopoietic stem cell transplantation. Impaired visual function, pain, and other …

Purpose: The metabolic alterations due to chronic hyperglycemia are well-known to cause
diabetes-associated complications. Short-term hyperglycemia has also been shown to …

Graft versus host disease (GVHD) remains a major and serious complication of allogeneic
hematopoietic stem cell transplantation. Based on the time of onset, clinical phenotypes …

Purpose: Lupus-like chronic graft-versus-host disease (cGVHD) has been previously
described, but the ocular findings have not been elucidated. Recipient mice in a lupus-like …

The ocular surface inflammatory disorders (OSIDs) comprise a group of conditions
characterized by persistent inflammation of the ocular surface and adnexal tissues. Systemic …

The present study is designed to investigate whether irradiation as used for conditioning
regimen to ablate recipient's diseased bone marrow prior to transplantation could trigger …