DNA-encoded chemical libraries (DELs) have emerged as a powerful technology in drug
discovery. The wide adoption of DELs in the pharmaceutical industry and the rapid …

A series of novel peptide‐based molecular probes for different biomarkers is highlighted
herein. These probes can provide targeted recognition with high affinity, high specificity …

Taking advantage of outstanding precision in target recognition and trans-cleavage ability,
the recently discovered CRISPR/Cas12a system provides an alternative opportunity for …

Synthetic polymers are highly customizable with tailored structures and functionality, yet this
versatility generates challenges in the design of advanced materials due to the size and …

Microbead-based point-of-care testing (POCT) has demonstrated great promise in
translating detection modalities from bench-side to bed-side. This is due to the ease of …

High-throughput assays play an important role in the fields of drug discovery, genetic
analysis, and clinical diagnostics. Although super-capacity coding strategies may facilitate …

Solid-phase peptide synthesis (SPPS) is usually performed with optically pure building
blocks to prepare peptides as single enantiomers. Herein we report that SPPS using …

Optical multiplex barcode systems have been significantly boosting the throughput of
scientific discovery. A high volume of barcodes can be made from combinations of distinct …

In addition to efficacious vaccines and antiviral therapeutics, reliable and flexible in-home
personal use diagnostics for the detection of viral antigens are needed for effective control of …

Combinatorial chemistry allows for the rapid synthesis of large compound libraries for high
throughput screenings in biology, medicinal chemistry, or materials science. Especially …