Placenta: the forgotten organ

E Maltepe, SJ Fisher - Annual review of cell and developmental …, 2015 - annualreviews.org
The placenta sits at the interface between the maternal and fetal vascular beds where it
mediates nutrient and waste exchange to enable in utero existence. Placental cells …

l-Carnitine and Acetyl-l-carnitine Roles and Neuroprotection in Developing Brain

GC Ferreira, MC McKenna - Neurochemical research, 2017 - Springer
Abstract l-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for
degradation by β-oxidation. Treatment with l-carnitine can ameliorate metabolic imbalances …

[HTML][HTML] Neuroprotective strategies after neonatal hypoxic ischemic encephalopathy

BJ Dixon, C Reis, WM Ho, J Tang… - International journal of …, 2015 - mdpi.com
Neonatal hypoxic ischemic encephalopathy (HIE) is a devastating disease that primarily
causes neuronal and white matter injury and is among the leading cause of death among …

Neuroprotective role of lactate in rat neonatal hypoxia-ischemia

H Roumes, U Dumont, S Sanchez… - Journal of Cerebral …, 2021 - journals.sagepub.com
Hypoxic-ischemic (HI) encephalopathy remains a major cause of perinatal mortality and
chronic disability in newborns worldwide (1–6 for 1000 births). The only current clinical …

Erythropoietin and neonatal neuroprotection

SE Juul, GC Pet - Clinics in perinatology, 2015 - perinatology.theclinics.com
Neonatology is a new field of medical practice, having come into its own in the 1960s. As the
practice has evolved, infants who were previously destined to die now survive, yet their …

[HTML][HTML] Comparing the efficacy in reducing brain injury of different neuroprotective agents following neonatal hypoxia–ischemia in newborn rats: a multi-drug …

H Sabir, E Maes, M Zweyer, Y Schleehuber… - Scientific Reports, 2023 - nature.com
Intrapartum hypoxia–ischemia leading to neonatal encephalopathy (NE) results in
significant neonatal mortality and morbidity worldwide, with> 85% of cases occurring in low …

[HTML][HTML] The potential role of ferroptosis in neonatal brain injury

Y Wu, J Song, Y Wang, X Wang, C Culmsee… - Frontiers in …, 2019 - frontiersin.org
Ferroptosis is an iron-dependent form of cell death that is characterized by early lipid
peroxidation and different from other forms of regulated cell death in terms of its genetic …

[HTML][HTML] Treatment of neonatal hypoxic-ischemic encephalopathy with erythropoietin alone, and erythropoietin combined with hypothermia: history, current status, and …

DE Oorschot, RJ Sizemore, AR Amer - International journal of molecular …, 2020 - mdpi.com
Perinatal hypoxic-ischemic encephalopathy (HIE) remains a major cause of morbidity and
mortality. Moderate hypothermia (33.5° C) is currently the sole established standard …

[HTML][HTML] Role of antioxidants in neonatal hypoxic–ischemic brain injury: new therapeutic approaches

O Arteaga, A Álvarez, M Revuelta… - International journal of …, 2017 - mdpi.com
Hypoxic–ischemic brain damage is an alarming health and economic problem in spite of the
advances in neonatal care. It can cause mortality or detrimental neurological disorders such …

The new antiepileptic drugs: their neuropharmacology and clinical indications

R Hanaya, K Arita - Neurologia medico-chirurgica, 2016 - jstage.jst.go.jp
The administration of antiepileptic drugs (AEDs) is the first treatment of epilepsy, one of the
most common neurological diseases. Therapeutic guidelines include newer AEDs as front …