[PDF][PDF] Broadening horizons: exploring mtDAMPs as a mechanism and potential intervention target in cardiovascular diseases

Y Luan, Y Luan, Y Jiao, H Liu, Z Huang, Q Feng… - Aging Dis, 2023 - researchgate.net
Cardiovascular diseases (CVDs) have been recognized as the leading cause of premature
mortality and morbidity worldwide despite significant advances in therapeutics. Inflammation …

Preclinical Study in Mouse Thymus and Thymocytes: Effects of Treatment with a Combination of Sodium Dichloroacetate and Sodium Valproate on Infectious …

D Stakišaitis, L Kapočius, E Kilimaitė, D Gečys… - Pharmaceutics, 2023 - mdpi.com
The research presents data from a preclinical study on the anti-inflammatory effects of a
sodium dichloroacetate and sodium valproate combination (DCA–VPA). The 2-week …

The metabolic footprint of Vero E6 cells highlights the key metabolic routes associated with SARS-CoV-2 infection and response to drug combinations

R Melis, A Braca, D Pagnozzi, R Anedda - Scientific Reports, 2024 - nature.com
SARS-CoV-2 burdens healthcare systems worldwide, yet specific drug-based treatments are
still unavailable. Understanding the effects of SARS-CoV-2 on host molecular pathways is …

Profiling endogenous adrenal function during veno-venous ECMO support in COVID-19 ARDS: a descriptive analysis

C Baumgartner, P Wolf, A Hermann, S König… - Frontiers in …, 2024 - frontiersin.org
Background Prolonged critical illness is often accompanied by an impairment of adrenal
function, which has been frequently related to conditions complicating patient management …

[PDF][PDF] Wedelolactone attenuates cerebral ischemia-reperfusion injury by blocking GPX4-mediated ferroptosis

H Yang, YW Dai Liu - Journal of Men's Health, 2023 - oss.jomh.org
Cerebral ischemia is currently the third leading cause of death worldwide. Among its
complications, cerebral ischemia-reperfusion (I/R) is considered the most inevitable …