Systematic review and meta-analysis of hypothermic machine perfusion versus static cold storage of kidney allografts on transplant outcomes

JM O'callaghan, RD Morgan, SR Knight… - Journal of British …, 2013 - academic.oup.com
Background Adequate preservation of renal allografts for transplantation is important for
maintaining and improving transplant outcomes. There are two prevalent methods …

Inflammatory signalling associated with brain dead organ donation: from brain injury to brain stem death and posttransplant ischaemia reperfusion injury

RP Watts, O Thom, JF Fraser - Journal of transplantation, 2013 - Wiley Online Library
Brain death is associated with dramatic and serious pathophysiologic changes that
adversely affect both the quantity and quality of organs available for transplant. To fully …

Oxygenated end-hypothermic machine perfusion in expanded criteria donor kidney transplant: a randomized clinical trial

P Husen, C Boffa, I Jochmans, C Krikke, L Davies… - JAMA …, 2021 - jamanetwork.com
Importance Continuous hypothermic machine perfusion during organ preservation has a
beneficial effect on graft function and survival in kidney transplant when compared with static …

[HTML][HTML] Past, present, and future of dynamic kidney and liver preservation and resuscitation

I Jochmans, MZ Akhtar, D Nasralla… - American Journal of …, 2016 - Elsevier
The increased demand for organs has led to the increased usage of “higher risk” kidney and
liver grafts. These grafts from donation after circulatory death or expanded criteria donors …

The benefits of hypothermic machine preservation and short cold ischemia times in deceased donor kidneys

J Kox, C Moers, D Monbaliu, A Strelniece… - …, 2018 - journals.lww.com
Background Hypothermic machine perfusion (HMP) of deceased donor kidneys is
associated with better outcome when compared to static cold storage (CS). Nevertheless …

Hypothermic machine perfusion of kidneys retrieved from standard and high‐risk donors

I Jochmans, JM O'Callaghan, J Pirenne… - Transplant …, 2015 - Wiley Online Library
Hypothermic machine perfusion (HMP) of kidneys is a long‐established alternative to static
cold storage and has been suggested to be a better preservation method. Today, as our …

[HTML][HTML] Maximizing kidneys for transplantation using machine perfusion: from the past to the future: A comprehensive systematic review and meta-analysis

AM Hameed, HC Pleass, G Wong, WJ Hawthorne - Medicine, 2016 - journals.lww.com
Background: The two main options for renal allograft preservation are static cold storage
(CS) and machine perfusion (MP). There has been considerably increased interest in MP …

Short, cool, and well oxygenated–HOPE for kidney transplantation in a rodent model

P Kron, A Schlegel, O de Rougemont… - Annals of …, 2016 - journals.lww.com
Objectives: The aim of this study was to investigate novel and easily applicable preservation
perfusion techniques in kidney grafts obtained from donors after circulatory death (DCD) …

Normothermic Ex Vivo Kidney Perfusion Following Static Cold Storage—Brief, Intermediate, or Prolonged Perfusion for Optimal Renal Graft Reconditioning?

JM Kaths, J Echeverri, I Linares, JY Cen… - American Journal of …, 2017 - Wiley Online Library
Normothermic ex vivo kidney perfusion (NEVKP) demonstrated superior results compared to
hypothermic storage in donation after circulatory death (DCD) kidney transplantation. It is …

[HTML][HTML] Pharmacologic targeting of renal ischemia-reperfusion injury using a normothermic machine perfusion platform

AM Hameed, DB Lu, H Burns, N Byrne, YV Chew… - Scientific Reports, 2020 - nature.com
Normothermic machine perfusion (NMP) is an emerging modality for kidney preservation
prior to transplantation. NMP may allow directed pharmacomodulation of renal ischemia …