Functional consequence of Iron dyshomeostasis and ferroptosis in systemic lupus erythematosus and lupus nephritis

L Morel, Y Scindia - Clinical Immunology, 2024 - Elsevier
Systemic lupus erythematosus (SLE) and its renal manifestation Lupus nephritis (LN) are
characterized by a dysregulated immune system, autoantibodies, and injury to the renal …

Iron homeostasis, recycling and vulnerability in the stressed kidney: A neglected dimension of iron‐deficient heart failure

M Packer - European Journal of Heart Failure, 2024 - Wiley Online Library
The available evidence suggests that the kidney may contribute importantly to the
development of an iron deficiency state in patients with heart failure and may be injured by …

Proteomics coupled transcriptomics reveals Slc34a1 and Slc34a3 downregulation as potential features of nephrotoxin-induced acute kidney injury

J Zhang, T Che, L Wang, W Sun, J Zhao, J Chen… - Journal of …, 2024 - Elsevier
Acute kidney injury (AKI) stands as a prevalent and economically burdensome condition
worldwide, yet its complex molecular mechanisms remain incompletely understood. To …

[PDF][PDF] Rusting from the inside: kidney-specific ferroportin deficiency and associated iron overload dictate susceptibility to acute kidney injury and fibrosis

Y Scindia - American Journal of Physiology-Renal …, 2024 - journals.physiology.org
Kidney fibrosis is the endpoint pathological outcome of chronic kidney disease (CKD), 16
whose morphological characteristics include glomerulosclerosis, tubular atrophy and 17 …

[HTML][HTML] Advances of iron and ferroptosis in diabetic kidney disease

J Chu, K Wang, L Lu, H Zhao, J Hu, W Xiao… - Kidney International …, 2024 - Elsevier
Diabetes mellitus presents a significant threat to human health as it disrupts energy
metabolism and gives rise to various complications, including diabetic kidney disease …