Recent advances in the biosynthesis, bioavailability, toxicology, pharmacology, and controlled release of citrus neohesperidin

S Akhter, MSI Arman, MA Tayab… - Critical Reviews in …, 2022 - Taylor & Francis
Abstract Neohesperidin (hesperetin 7-O-neohesperidoside), a well-known flavanone
glycoside widely found in citrus fruits, exhibits a variety of biological activities, with potential …

Analysis and occurrence of seven artificial sweeteners in German waste water and surface water and in soil aquifer treatment (SAT)

M Scheurer, HJ Brauch, FT Lange - Analytical and Bioanalytical Chemistry, 2009 - Springer
A method for the simultaneous determination of seven commonly used artificial sweeteners
in water is presented. The analytes were extracted by solid phase extraction using …

[HTML][HTML] Dietary chalcones with chemopreventive and chemotherapeutic potential

B Orlikova, D Tasdemir, F Golais, M Dicato… - Genes & nutrition, 2011 - Springer
Chalcones are absorbed in the daily diet and appear to be promising cancer
chemopreventive agents. Chalcones represent an important group of the polyphenolic …

Evaluation and discovery of novel synthetic chalcone derivatives as anti-inflammatory agents

J Wu, J Li, Y Cai, Y Pan, F Ye, Y Zhang… - Journal of medicinal …, 2011 - ACS Publications
Major anti-inflammatory agents, steroids and cyclooxygenase, were proved to have serious
side effects. Here, a series of chalcone derivatives were synthesized and screened for anti …

Critical considerations for developing nucleic acid macromolecule based drug products

BK Muralidhara, R Baid, SM Bishop, M Huang… - Drug discovery today, 2016 - Elsevier
Highlights•Increased emphasis in recent years on DNA/mRNA macromolecule-based
therapeutic drugs.•Formulation excipients and their role in increasing the drug product …

Neuroprotective Effects of the Citrus Flavanones against H2O2-Induced Cytotoxicity in PC12 Cells

SL Hwang, GC Yen - Journal of agricultural and food chemistry, 2008 - ACS Publications
The citrus flavanones hesperidin, hesperetin, and neohesperidin are known to exhibit
antioxidant activities and could traverse the blood-brain barrier. H2O2 formation induces …

[HTML][HTML] Antioxidant structure–activity relationship analysis of five dihydrochalcones

X Li, B Chen, H Xie, Y He, D Zhong, D Chen - Molecules, 2018 - mdpi.com
The study determined the comparative antioxidant capacities of five similar
dihydrochalcones: phloretin, phloridzin, trilobatin, neohesperidin dihydrochalcone, and …

Investigation of neohesperidin dihydrochalcone binding to human serum albumin by spectroscopic methods

BK Bozoğlan, S Tunç, O Duman - Journal of Luminescence, 2014 - Elsevier
In this study, the interaction of human serum albumin (HSA) with neohesperidin
dihydrochalcone (NHD) was investigated by UV, fluorescence, synchronous fluorescence …

Comparison of interaction between three similar chalconoids and α-lactalbumin: Impact on structure and functionality of α-lactalbumin

Z Jiang, T Li, L Ma, W Chen, H Yu, Q Abdul… - Food research …, 2020 - Elsevier
Interaction between α-lactalbumin (α-LA) and three similar chalconoids was compared using
a combination of multi-spectral analysis and molecular docking, and their influence on …

Neohesperidin dihydrochalcone ameliorates high-fat diet-induced glycolipid metabolism disorder in rats

Y Xiao, D Su, X Hu, G Yang, Y Shan - Journal of Agricultural and …, 2022 - ACS Publications
High-fat diet (HFD) is closely related to the formation of metabolic diseases. Studies have
confirmed that neohesperidin dihydrochalcone (NHDC) possesses the biological activity of …