[HTML][HTML] Therapeutic effects of green tea polyphenol (‒)-Epigallocatechin-3-Gallate (EGCG) in relation to molecular pathways controlling inflammation, oxidative stress …

D Mokra, M Joskova, J Mokry - International journal of molecular sciences, 2022 - mdpi.com
(‒)-Epigallocatechin-3-gallate (EGCG) is the most abundant polyphenol in green tea.
Thanks to multiple interactions with cell surface receptors, intracellular signaling pathways …

[HTML][HTML] Oxidative stress is a key modulator in the development of nonalcoholic fatty liver disease

Y Ma, G Lee, SY Heo, YS Roh - Antioxidants, 2021 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease
worldwide, and scientific studies consistently report that NAFLD development can be …

[HTML][HTML] Skin pigmentation types, causes and treatment—a review

AM Thawabteh, A Jibreen, D Karaman, A Thawabteh… - Molecules, 2023 - mdpi.com
Human skin pigmentation and melanin synthesis are incredibly variable, and are impacted
by genetics, UV exposure, and some drugs. Patients' physical appearance, psychological …

[HTML][HTML] The role of natural products and their multitargeted approach to treat solid cancer

N Muhammad, D Usmani, M Tarique, H Naz, M Ashraf… - Cells, 2022 - mdpi.com
Natural products play a critical role in the discovery and development of numerous drugs for
the treatment of various types of cancer. These phytochemicals have demonstrated anti …

Chemico-biological aspects of (−)-epigallocatechin-3-gallate (EGCG) to improve its stability, bioavailability and membrane permeability: Current status and future …

R Sahadevan, S Singh, A Binoy… - Critical Reviews in Food …, 2023 - Taylor & Francis
Natural products have been a bedrock for drug discovery for decades.(−)-Epigallocatechin-3-
gallate (EGCG) is one of the widely studied natural polyphenolic compounds derived from …

Chinese herbal medicines: The modulator of nonalcoholic fatty liver disease targeting oxidative stress

P Gong, H Long, Y Guo, Z Wang, W Yao, J Wang… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Plants are a natural treasure trove; their secondary
metabolites participate in several pharmacological processes, making them a crucial …

Regulatory effects and molecular mechanisms of tea and its active compounds on nonalcoholic fatty liver disease

J Xu, Y Wei, Y Huang, X Wei - Journal of Agricultural and Food …, 2023 - ACS Publications
Nonalcoholic fatty liver disease (NAFLD), the most common chronic liver disease, is a
multifactorial disease resulting from the interaction between environment, genetic …

[HTML][HTML] Therapeutic activity of green tea epigallocatechin-3-gallate on metabolic diseases and non-alcoholic fatty liver diseases: The current updates

A James, K Wang, Y Wang - Nutrients, 2023 - mdpi.com
Green tea polyphenols have numerous functions including antioxidation and modulation of
various cellular proteins and are thus beneficial against metabolic diseases including …

[HTML][HTML] Efficacy and safety of dietary polyphenol supplementation in the treatment of non-alcoholic fatty liver disease: A systematic review and meta-analysis

K Yang, J Chen, T Zhang, X Yuan, A Ge… - Frontiers in …, 2022 - frontiersin.org
Background Dietary polyphenol treatment of non-alcoholic fatty liver disease (NAFLD) is a
novel direction, and the existing clinical studies have little effective evidence for its …

[HTML][HTML] Epigallocatechin gallate alleviates high-fat diet-induced hepatic lipotoxicity by targeting mitochondrial ROS-mediated ferroptosis

SB Ding, XL Chu, YX Jin, JJ Jiang, X Zhao… - Frontiers in …, 2023 - frontiersin.org
Background: Non-alcoholic fatty liver disease (NAFLD) is a chronic advanced liver disease
that is highly related to metabolic disorders and induced by a high-fat diet (HFD). Recently …