Simple Summary Head and neck cancer remains a challenging and deadly disease as it is
often identified in more advanced stages due to limitations in screening and surveillance …

Body fluids of patients with head and neck squamous cell carcinoma (HNSCC) are enriched
in exosomes that reflect properties of the tumor. The aim of this study was to determine …

The primary cause of mortality among patients with cancer is the progression of the tumor,
better known as cancer invasion and metastasis. Cancer progression involves a series of …

Metastatic diffusion is thought to be a multi-step phenomenon involving the release of cells
from the primary tumor and their diffusion through the body. Currently, several hypotheses …

Cancer progression impacts and exploits the vascular system in several highly
consequential ways. Among different types of vascular cells, blood cells and mediators that …

Pancreatic cancer (PC) is one of the most aggressive cancers in the world. Several
extracellular factors are involved in its development and metastasis to distant organs. In PC …

Exosomes are small membranous vesicles that contain proteins, lipids, genetic material, and
metabolites with abundant information from parental cells. Exosomes carry and deliver …

Glioblastoma multiform (GBM) is a highly aggressive primary brain tumor. Exosomes derived
from glioma cells under a hypoxic microenvironment play an important role in tumor biology …

Blood vessels deliver oxygen and nutrients that sustain tumor growth and enable the
dissemination of cancer cells to distant sites and the recruitment of intratumoral immune …

Head and neck squamous cell carcinomas (HNSCCs) are aggressive and clinically
challenging tumours that require a multidisciplinary management approach. Despite …