MicroRNAs: Their role in metabolism, tumor microenvironment, and therapeutic implications in head and neck squamous cell carcinoma
SG Shiah, ST Chou, JY Chang - Cancers, 2021 - mdpi.com
Simple Summary Head and neck squamous cell carcinoma (HNSCC), which arises from the
oral epithelium, is one of the most common cancers worldwide. Despite excellent diagnosis …
oral epithelium, is one of the most common cancers worldwide. Despite excellent diagnosis …
Lack of miR‐1246 in small extracellular vesicle blunts tumorigenesis of laryngeal carcinoma cells by regulating Cyclin G2
Q Huang, CY Hsueh, Y Guo, XF Wu, JY Li, L Zhou - IUBMB life, 2020 - Wiley Online Library
Small extracellular vesicle (sEV) has precise impacts on tumor microenvironment and play
vital functions in intercellular interaction. However, the functional role of sEV miRNA on …
vital functions in intercellular interaction. However, the functional role of sEV miRNA on …
Exosomal cargoes in OSCC: current findings and potential functions
C Zhao, G Zhang, J Liu, C Zhang, Y Yao, W Liao - PeerJ, 2020 - peerj.com
Oral squamous cell carcinoma (OSCC) is the most prevalent malignancy in head and neck
cancer, with high recurrence and mortality. Early diagnosis and efficient therapeutic …
cancer, with high recurrence and mortality. Early diagnosis and efficient therapeutic …
Developing a dual VEGF/PDL1 inhibitor based on high-affinity scFv heterodimers as an anti-cancer therapeutic strategy
N Tzuri, KM Yegodayev, O Novoplansky, M Elkabets… - Scientific Reports, 2023 - nature.com
Cancer progression is enhanced by the interaction of programmed death-ligand 1 (PDL1),
which is associated with inhibition of the immune response against tumors, and vascular …
which is associated with inhibition of the immune response against tumors, and vascular …
Pro-angiogenic effect of PC-3 exosomes in endothelial cells in vitro
AN Prigol, MP Rode, AH Silva, J Cisilotto… - Cellular …, 2021 - Elsevier
The progression to a castration-resistant prostate cancer can occur after treatment with
androgen deprivation therapy, resulting in poor prognosis and ineffective therapy response …
androgen deprivation therapy, resulting in poor prognosis and ineffective therapy response …
Potential roles of tumor cell-and stroma cell-derived small extracellular vesicles in promoting a pro-angiogenic tumor microenvironment
N Ludwig, DS Rubenich, Ł Zaręba, J Siewiera, J Pieper… - Cancers, 2020 - mdpi.com
Simple Summary In this review, we focus on the distinct functions of tumor-cell-derived small
extracellular vesicles in promotion of angiogenesis and describe their potential as a …
extracellular vesicles in promotion of angiogenesis and describe their potential as a …
Tumor-derived exosomes: hidden players in PD-1/PD-L1 resistance
V Vautrot, H Bentayeb, S Causse, C Garrido, J Gobbo - Cancers, 2021 - mdpi.com
Simple Summary Immunotherapies such as anti-PD-1/PD-L1 have garnered increasing
importance in cancer therapy, leading to substantial improvements in patient care and …
importance in cancer therapy, leading to substantial improvements in patient care and …
Unfolded protein response and angiogenesis in malignancies
A Izadpanah, K Willingham, B Chandrasekar… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Cellular stress, arising from accumulation of unfolded proteins, occurs frequently in rapidly
proliferating cancer cells. This cellular stress, in turn, activates the unfolded protein response …
proliferating cancer cells. This cellular stress, in turn, activates the unfolded protein response …
Mechanisms driving palmitate-mediated neuronal dysregulation in the hypothalamus
CV Lieu, N Loganathan, DD Belsham - Cells, 2021 - mdpi.com
The hypothalamus maintains whole-body homeostasis by integrating information from
circulating hormones, nutrients and signaling molecules. Distinct neuronal subpopulations …
circulating hormones, nutrients and signaling molecules. Distinct neuronal subpopulations …
Human Papillomavirus-Associated Tumor Extracellular Vesicles in HPV+ Tumor Microenvironments
SF Gameiro, KM Flondra - Journal of Clinical Medicine, 2023 - mdpi.com
Most infections with human papillomaviruses (HPVs) are self-resolving and asymptomatic.
However, some infections can lead to the development of cancer at different mucosal sites …
However, some infections can lead to the development of cancer at different mucosal sites …